Effects of palbociclib in oral squamous cell carcinoma and the role of PIK3CA in conferring resistance

Effects of palbociclib in oral squamous cell carcinoma and the role of PIK3CA in conferring resistance

Objective: Lack of effective therapies remains a problem in the treatment of oral squamous cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is driven by multiple aberrancies within the cell cycle pathway, including amplification of cyclin D1 and loss of p16. Hence...

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Bibliographic Details
Main Authors:	Zainal, Nur Syafinaz, Lee, Bernard Kok Bang, Wong, Zheng Wei, Chin, Iuan Sheau, Yee, Pei San, Gan, Chai Phei, Mun, Kein Seong, Rahman, Zainal Ariff Abdul, Gutkind, J. Silvio, Patel, Vyomesh, Cheong, Sok Ching
Format:	Article
Language:	English
Published:	Chinese Anti-cancer Association 2019
Subjects:	R Medicine RC Internal medicine RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Online Access:	http://eprints.um.edu.my/23892/1/cbm-16-2-264.pdf

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