Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization
Green synthesis methods are considered as a safer alternative to the conventional synthetic processes due to their eco-friendly nature, cost-effectiveness, and easy handling. In the present study, an eco-friendly and sustainable method for the synthesis of stable arenediazonium has been developed us...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Published: |
De Gruyter
2019
|
| Subjects: |
| _version_ | 1796961979053637632 |
|---|---|
| author | Khaligh, Nader Ghaffari Johan, Mohd Rafie Juan, Joon Ching |
| author_facet | Khaligh, Nader Ghaffari Johan, Mohd Rafie Juan, Joon Ching |
| author_sort | Khaligh, Nader Ghaffari |
| collection | UM |
| description | Green synthesis methods are considered as a safer alternative to the conventional synthetic processes due to their eco-friendly nature, cost-effectiveness, and easy handling. In the present study, an eco-friendly and sustainable method for the synthesis of stable arenediazonium has been developed using saccharin as a cheap and mild acidic agent and tert-butyl nitrite as a diazotization reagent for the first time. These stable intermediates were used in the azo coupling reaction with 4-hydroxybenzaldehyde via telescoped dediazotization. The current method has advantages such as reduced waste by avoiding solvent for the purification of intermediate in diazotization step, cost-effectiveness, simple experimental procedure, good yield of azo dyes, metal-free waste, and environmentally benign conditions. An interesting aspect of this study is the recovery of saccharin from the reaction, which could be reused. © 2019 Walter de Gruyter GmbH, Berlin/Boston. |
| first_indexed | 2024-03-06T06:02:11Z |
| format | Article |
| id | um.eprints-24232 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T06:02:11Z |
| publishDate | 2019 |
| publisher | De Gruyter |
| record_format | dspace |
| spelling | um.eprints-242322020-04-23T14:47:18Z http://eprints.um.edu.my/24232/ Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization Khaligh, Nader Ghaffari Johan, Mohd Rafie Juan, Joon Ching QD Chemistry Green synthesis methods are considered as a safer alternative to the conventional synthetic processes due to their eco-friendly nature, cost-effectiveness, and easy handling. In the present study, an eco-friendly and sustainable method for the synthesis of stable arenediazonium has been developed using saccharin as a cheap and mild acidic agent and tert-butyl nitrite as a diazotization reagent for the first time. These stable intermediates were used in the azo coupling reaction with 4-hydroxybenzaldehyde via telescoped dediazotization. The current method has advantages such as reduced waste by avoiding solvent for the purification of intermediate in diazotization step, cost-effectiveness, simple experimental procedure, good yield of azo dyes, metal-free waste, and environmentally benign conditions. An interesting aspect of this study is the recovery of saccharin from the reaction, which could be reused. © 2019 Walter de Gruyter GmbH, Berlin/Boston. De Gruyter 2019 Article PeerReviewed Khaligh, Nader Ghaffari and Johan, Mohd Rafie and Juan, Joon Ching (2019) Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization. Green Processing and Synthesis, 8 (1). pp. 24-29. ISSN 2191-9542, DOI https://doi.org/10.1515/gps-2017-0133 <https://doi.org/10.1515/gps-2017-0133>. https://doi.org/10.1515/gps-2017-0133 doi:10.1515/gps-2017-0133 |
| spellingShingle | QD Chemistry Khaligh, Nader Ghaffari Johan, Mohd Rafie Juan, Joon Ching Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization |
| title | Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization |
| title_full | Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization |
| title_fullStr | Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization |
| title_full_unstemmed | Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization |
| title_short | Saccharin: a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization |
| title_sort | saccharin a cheap and mild acidic agent for the synthesis of azo dyes via telescoped dediazotization |
| topic | QD Chemistry |
| work_keys_str_mv | AT khalighnaderghaffari saccharinacheapandmildacidicagentforthesynthesisofazodyesviatelescopeddediazotization AT johanmohdrafie saccharinacheapandmildacidicagentforthesynthesisofazodyesviatelescopeddediazotization AT juanjoonching saccharinacheapandmildacidicagentforthesynthesisofazodyesviatelescopeddediazotization |