1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae)
The title compound (trivial name: angustoline monohydrate), C20H17N3O2 H2O, features a fused-ring system formed by one five- and four six-membered rings. The nearly planar benzimidazole portion (r.m.s. deviation = 0.008 A˚) and the nearly planar 2,7-naphthyridin-1-one portion (r.m.s. deviation = 0...
| Hoofdauteurs: | , , , , |
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| Formaat: | Artikel |
| Taal: | English |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | http://eprints.um.edu.my/2430/1/1-%281-Hydroxyethyl%29-7%2C_8-dihydroindolo_%5B2%2C_3-a%5D_pyridine_%5B3%2C_4-g%5D_quinolizin-5_%2813H%29-one_%28angustoline%29_monohydrate_from_Nauclea_subdita_%28Rubiaceae%29.pdf |
| _version_ | 1825718676578369536 |
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| author | Liew, Sook Yee Mukhtar, Mat Ropi Awang, Khalijah Mustafa, Mohd Rais Ng, Seik Weng |
| author_facet | Liew, Sook Yee Mukhtar, Mat Ropi Awang, Khalijah Mustafa, Mohd Rais Ng, Seik Weng |
| author_sort | Liew, Sook Yee |
| collection | UM |
| description | The title compound (trivial name: angustoline monohydrate),
C20H17N3O2 H2O, features a fused-ring system formed by one
five- and four six-membered rings. The nearly planar
benzimidazole portion (r.m.s. deviation = 0.008 A˚) and the nearly planar 2,7-naphthyridin-1-one portion (r.m.s. deviation = 0.022 A˚) of the fused-ring system are slightly twisted, with a dihedral angle of 9.47 (8), owing to the tetrahedral nature of the two methylene linkages in the central six-membered ring. The secondary N atom acts as a hydrogen-bond donor to the water molecule of crystallization. In the crystal, the amino and hydroxy groups, and the water molecule are engaged in
hydrogen bonding, generating a three-dimensional network. |
| first_indexed | 2024-03-06T05:08:02Z |
| format | Article |
| id | um.eprints-2430 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:08:02Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | um.eprints-24302019-12-18T06:36:15Z http://eprints.um.edu.my/2430/ 1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae) Liew, Sook Yee Mukhtar, Mat Ropi Awang, Khalijah Mustafa, Mohd Rais Ng, Seik Weng QD Chemistry The title compound (trivial name: angustoline monohydrate), C20H17N3O2 H2O, features a fused-ring system formed by one five- and four six-membered rings. The nearly planar benzimidazole portion (r.m.s. deviation = 0.008 A˚) and the nearly planar 2,7-naphthyridin-1-one portion (r.m.s. deviation = 0.022 A˚) of the fused-ring system are slightly twisted, with a dihedral angle of 9.47 (8), owing to the tetrahedral nature of the two methylene linkages in the central six-membered ring. The secondary N atom acts as a hydrogen-bond donor to the water molecule of crystallization. In the crystal, the amino and hydroxy groups, and the water molecule are engaged in hydrogen bonding, generating a three-dimensional network. 2011-06-13 Article PeerReviewed application/pdf en http://eprints.um.edu.my/2430/1/1-%281-Hydroxyethyl%29-7%2C_8-dihydroindolo_%5B2%2C_3-a%5D_pyridine_%5B3%2C_4-g%5D_quinolizin-5_%2813H%29-one_%28angustoline%29_monohydrate_from_Nauclea_subdita_%28Rubiaceae%29.pdf Liew, Sook Yee and Mukhtar, Mat Ropi and Awang, Khalijah and Mustafa, Mohd Rais and Ng, Seik Weng (2011) 1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae). Acta Crystallographica Section E: Structure Reports Online, 67 (7). o1727-o1728. ISSN 1600-5368, DOI https://doi.org/10.1107/S1600536811022768 <https://doi.org/10.1107/S1600536811022768>. doi:10.1107/S1600536811022768 |
| spellingShingle | QD Chemistry Liew, Sook Yee Mukhtar, Mat Ropi Awang, Khalijah Mustafa, Mohd Rais Ng, Seik Weng 1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae) |
| title | 1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae) |
| title_full | 1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae) |
| title_fullStr | 1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae) |
| title_full_unstemmed | 1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae) |
| title_short | 1-(1-Hydroxyethyl)-7, 8-dihydroindolo [2, 3-a] pyridine [3, 4-g] quinolizin-5 (13H)-one (angustoline) monohydrate from Nauclea subdita (Rubiaceae) |
| title_sort | 1 1 hydroxyethyl 7 8 dihydroindolo 2 3 a pyridine 3 4 g quinolizin 5 13h one angustoline monohydrate from nauclea subdita rubiaceae |
| topic | QD Chemistry |
| url | http://eprints.um.edu.my/2430/1/1-%281-Hydroxyethyl%29-7%2C_8-dihydroindolo_%5B2%2C_3-a%5D_pyridine_%5B3%2C_4-g%5D_quinolizin-5_%2813H%29-one_%28angustoline%29_monohydrate_from_Nauclea_subdita_%28Rubiaceae%29.pdf |
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