Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells
Background: Alpha-tomatine (a-tomatine) is the major saponin in tomato (Lycopersicon esculentum). This study investigates the chemopreventive potential of a-tomatine on androgen-independent human prostatic adenocarcinoma PC-3 cells. Methodology/Principal Findings: Treatment of highly aggressive...
Main Authors: | Lee, S.T., Wong, P.F., Cheah, S.C., Mustafa, Mohd Rais |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science
2011
|
Subjects: | |
Online Access: | http://eprints.um.edu.my/2440/1/journal.pone.0018915.pdf |
Similar Items
-
Alpha-tomatine induces apoptosis and inhibits nuclear factor-kappa B activation on human prostatic adenocarcinoma PC-3 cells.
by: Sui-Ting Lee, et al.
Published: (2011-01-01) -
Panduratin A, a possible inhibitor in metastasized A549 cells through inhibition of NF-Kappa B Translocation and chemoinvasion
by: Cheah, Shiau Chuen, et al.
Published: (2013) -
Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways
by: Looi, C.Y., et al.
Published: (2013) -
Effects of ascorbic acid on impaired vascular reactivity in aortas isolated from age-matched hypertensive and diabetic rats
by: Ajay, M., et al.
Published: (2006) -
Chronic treatment with flavonoids prevents endothelial dysfunction in spontaneously hypertensive rat aorta
by: Ajay, M., et al.
Published: (2005)