The invitro hippocampal slice technique as a tool for studying the central nervous system

The use of brain slice preparations has become increasingly popular among scientists of different disciplines in recent decades for the study of the mammalian central nervous system (CNS) in general and of synaptic phenomena in particular. The in vitro hippocampal slice may be the single most used p...

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Main Authors: El-Sabban, Farouk, Aziz, Zoriah, Murgan, Vidhya
Format: Article
Published: Faculty of Medicine, University of Malaya 2000
Subjects:
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author El-Sabban, Farouk
Aziz, Zoriah
Murgan, Vidhya
author_facet El-Sabban, Farouk
Aziz, Zoriah
Murgan, Vidhya
author_sort El-Sabban, Farouk
collection UM
description The use of brain slice preparations has become increasingly popular among scientists of different disciplines in recent decades for the study of the mammalian central nervous system (CNS) in general and of synaptic phenomena in particular. The in vitro hippocampal slice may be the single most used preparation, among other slices of different parts of the brain areas. The use of brain slices in different experimental work offers certain advantages over the in vivo approaches to the study of the CNS; however, such preparations may have some limitations. This review describes the hippocampal slice technique, explores some of the different types of studies in which it was employed and points out the advantages and limitations of its use.
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spelling um.eprints-244632020-06-02T05:03:55Z http://eprints.um.edu.my/24463/ The invitro hippocampal slice technique as a tool for studying the central nervous system El-Sabban, Farouk Aziz, Zoriah Murgan, Vidhya R Medicine The use of brain slice preparations has become increasingly popular among scientists of different disciplines in recent decades for the study of the mammalian central nervous system (CNS) in general and of synaptic phenomena in particular. The in vitro hippocampal slice may be the single most used preparation, among other slices of different parts of the brain areas. The use of brain slices in different experimental work offers certain advantages over the in vivo approaches to the study of the CNS; however, such preparations may have some limitations. This review describes the hippocampal slice technique, explores some of the different types of studies in which it was employed and points out the advantages and limitations of its use. Faculty of Medicine, University of Malaya 2000-06 Article PeerReviewed El-Sabban, Farouk and Aziz, Zoriah and Murgan, Vidhya (2000) The invitro hippocampal slice technique as a tool for studying the central nervous system. Journal of the University of Malaya Medical Centre (JUMMEC), 5 (1). pp. 17-23. ISSN 1823-7339, https://jummec.um.edu.my/article/view/4454
spellingShingle R Medicine
El-Sabban, Farouk
Aziz, Zoriah
Murgan, Vidhya
The invitro hippocampal slice technique as a tool for studying the central nervous system
title The invitro hippocampal slice technique as a tool for studying the central nervous system
title_full The invitro hippocampal slice technique as a tool for studying the central nervous system
title_fullStr The invitro hippocampal slice technique as a tool for studying the central nervous system
title_full_unstemmed The invitro hippocampal slice technique as a tool for studying the central nervous system
title_short The invitro hippocampal slice technique as a tool for studying the central nervous system
title_sort invitro hippocampal slice technique as a tool for studying the central nervous system
topic R Medicine
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