Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens
Two different preparations of monoclonal antibodies developed against respiratory viruses have been evaluated by the immunofluorescence antibody technique. The Chemicon monoclonal antibodies were found to be more efTicient at picking up positive specimens with a high sensitivity and specificity than...
| Main Author: | |
|---|---|
| Format: | Article |
| Published: |
Faculty of Medicine, University of Malaya
1996
|
| Subjects: |
| _version_ | 1825722257189634048 |
|---|---|
| author | Khairullah, N.S. |
| author_facet | Khairullah, N.S. |
| author_sort | Khairullah, N.S. |
| collection | UM |
| description | Two different preparations of monoclonal antibodies developed against respiratory viruses have been evaluated by the immunofluorescence antibody technique. The Chemicon monoclonal antibodies were found to be more efTicient at picking up positive specimens with a high sensitivity and specificity than Imagen monoclonal antibodies. However, the overall concordance rate of the monoclonal antibodies was 92.3%-100%. Generally, when compared with cell culture isolation, the immunofluorescence antibody technique was found to be more sensitive. The high quality of the Chemicon monoclonal antibodies contribute to their value in providing definitive diagnosis, within a few hours of specimen collection, thus allowing early management of patients, their contacts and control of hospital infection. |
| first_indexed | 2024-03-06T06:02:54Z |
| format | Article |
| id | um.eprints-24485 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T06:02:54Z |
| publishDate | 1996 |
| publisher | Faculty of Medicine, University of Malaya |
| record_format | dspace |
| spelling | um.eprints-244852021-03-24T01:43:37Z http://eprints.um.edu.my/24485/ Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens Khairullah, N.S. R Medicine Two different preparations of monoclonal antibodies developed against respiratory viruses have been evaluated by the immunofluorescence antibody technique. The Chemicon monoclonal antibodies were found to be more efTicient at picking up positive specimens with a high sensitivity and specificity than Imagen monoclonal antibodies. However, the overall concordance rate of the monoclonal antibodies was 92.3%-100%. Generally, when compared with cell culture isolation, the immunofluorescence antibody technique was found to be more sensitive. The high quality of the Chemicon monoclonal antibodies contribute to their value in providing definitive diagnosis, within a few hours of specimen collection, thus allowing early management of patients, their contacts and control of hospital infection. Faculty of Medicine, University of Malaya 1996-12 Article PeerReviewed Khairullah, N.S. (1996) Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens. Journal of the University of Malaya Medical Centre (JUMMEC), 1 (2). p. 58. ISSN 1823-7339, https://jummec.um.edu.my/issue/view/661/Vol.1%2C%20No.2%2C%201996 |
| spellingShingle | R Medicine Khairullah, N.S. Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens |
| title | Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens |
| title_full | Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens |
| title_fullStr | Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens |
| title_full_unstemmed | Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens |
| title_short | Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens |
| title_sort | comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens |
| topic | R Medicine |
| work_keys_str_mv | AT khairullahns comparisonoftwomonoclonalantibodykitswithcellcultureisolationinthedetectionofrespiratoryvirusantigens |