The use of mycophenolate mofetil in treating patients with non responding aplastic anemia
Aplastic anemia is a relatively uncommon disease and conventional management options include immunosuppressive drugs and/or haematopoeitic stem cell transplantation. It is now known that the pathogenesis of aplastic anemia is immune mediated. Mycophenolate mofetil is a common immunosuppressive drug...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Malaysian Medical Association
2005
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| Online Access: | http://eprints.um.edu.my/24590/1/Aplastic_Anemia.pdf |
| _version_ | 1825722276964728832 |
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| author | Gan, Gin Gin Leong, C.F. Sangkar, J.V. Teh, A. Goh, K.Y. Cheong, S.K. |
| author_facet | Gan, Gin Gin Leong, C.F. Sangkar, J.V. Teh, A. Goh, K.Y. Cheong, S.K. |
| author_sort | Gan, Gin Gin |
| collection | UM |
| description | Aplastic anemia is a relatively uncommon disease and conventional management options include immunosuppressive drugs and/or haematopoeitic stem cell transplantation. It is now known that the pathogenesis of aplastic anemia is immune mediated. Mycophenolate mofetil is a common immunosuppressive drug now used mainly in prophylaxis of graft rejection in organ transplant and also for prevention/treatment for graft versus host disease in haemtopoeitic stem cell transplantation. It is thought that mycophenolate mofetil may be useful in this group of patients. In this short report, mycophenolate mofetil was tried in 6 patients who had severe aplastic anemia with variable doses for a minimum duration of 9 months. The result has however not been encouraging. |
| first_indexed | 2024-03-06T06:03:12Z |
| format | Article |
| id | um.eprints-24590 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T06:03:12Z |
| publishDate | 2005 |
| publisher | Malaysian Medical Association |
| record_format | dspace |
| spelling | um.eprints-245902020-06-03T06:58:22Z http://eprints.um.edu.my/24590/ The use of mycophenolate mofetil in treating patients with non responding aplastic anemia Gan, Gin Gin Leong, C.F. Sangkar, J.V. Teh, A. Goh, K.Y. Cheong, S.K. R Medicine Aplastic anemia is a relatively uncommon disease and conventional management options include immunosuppressive drugs and/or haematopoeitic stem cell transplantation. It is now known that the pathogenesis of aplastic anemia is immune mediated. Mycophenolate mofetil is a common immunosuppressive drug now used mainly in prophylaxis of graft rejection in organ transplant and also for prevention/treatment for graft versus host disease in haemtopoeitic stem cell transplantation. It is thought that mycophenolate mofetil may be useful in this group of patients. In this short report, mycophenolate mofetil was tried in 6 patients who had severe aplastic anemia with variable doses for a minimum duration of 9 months. The result has however not been encouraging. Malaysian Medical Association 2005 Article PeerReviewed text en http://eprints.um.edu.my/24590/1/Aplastic_Anemia.pdf Gan, Gin Gin and Leong, C.F. and Sangkar, J.V. and Teh, A. and Goh, K.Y. and Cheong, S.K. (2005) The use of mycophenolate mofetil in treating patients with non responding aplastic anemia. Medical Journal of Malaysia, 60 (3). pp. 311-313. ISSN 0300-5283, http://www.e-mjm.org/2005/v60n3/Aplastic_Anemia.pdf |
| spellingShingle | R Medicine Gan, Gin Gin Leong, C.F. Sangkar, J.V. Teh, A. Goh, K.Y. Cheong, S.K. The use of mycophenolate mofetil in treating patients with non responding aplastic anemia |
| title | The use of mycophenolate mofetil in treating patients with non responding aplastic anemia |
| title_full | The use of mycophenolate mofetil in treating patients with non responding aplastic anemia |
| title_fullStr | The use of mycophenolate mofetil in treating patients with non responding aplastic anemia |
| title_full_unstemmed | The use of mycophenolate mofetil in treating patients with non responding aplastic anemia |
| title_short | The use of mycophenolate mofetil in treating patients with non responding aplastic anemia |
| title_sort | use of mycophenolate mofetil in treating patients with non responding aplastic anemia |
| topic | R Medicine |
| url | http://eprints.um.edu.my/24590/1/Aplastic_Anemia.pdf |
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