The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia

Malaysia is a non-endemic country for hepatitis E virus (HEV) infection. However, seroprevalence as high as 50% among samples of aboriginal people were reported over two decades ago. A total of 207 samples collected from seven aboriginal villages in rural settlements across two states in Malaysia we...

Full description

Bibliographic Details
Main Authors: Wong, Li Ping, Alias, Haridah, Choy, Seow Huey, Goh, Xiang Ting, Lee, Soo Ching, Lim, Yvonne Ai Lian, Kee, Boon Pin, Chua, Kek Heng, Kamarulzaman, Adeeba, Zheng, Zizheng, Zhao, Qinjian, Wu, Ting
Format: Article
Published: Wiley 2020
Subjects:
_version_ 1796962085607833600
author Wong, Li Ping
Alias, Haridah
Choy, Seow Huey
Goh, Xiang Ting
Lee, Soo Ching
Lim, Yvonne Ai Lian
Kee, Boon Pin
Chua, Kek Heng
Kamarulzaman, Adeeba
Zheng, Zizheng
Zhao, Qinjian
Wu, Ting
author_facet Wong, Li Ping
Alias, Haridah
Choy, Seow Huey
Goh, Xiang Ting
Lee, Soo Ching
Lim, Yvonne Ai Lian
Kee, Boon Pin
Chua, Kek Heng
Kamarulzaman, Adeeba
Zheng, Zizheng
Zhao, Qinjian
Wu, Ting
author_sort Wong, Li Ping
collection UM
description Malaysia is a non-endemic country for hepatitis E virus (HEV) infection. However, seroprevalence as high as 50% among samples of aboriginal people were reported over two decades ago. A total of 207 samples collected from seven aboriginal villages in rural settlements across two states in Malaysia were analysed for anti-HEV IgG and IgM by an enzyme-linked immunoassay. Following the detection of anti-HEV seroprevalence, we organized health outreach to inform and educate the community. Qualitative interviews were conducted with individuals tested positive for anti-HEV antibodies. Data derived from interviews and observations were used to investigate possible lifestyle behaviours associated with HEV infection. Anti-HEV IgG was detected in six samples (5.9%) from the village of Dusun Kubur. Qualitative inquiry and observation study revealed poor dietary and household hygiene, contaminated food and water, contact with animal faeces, unsanitary and domestic waste disposal, and wildlife reservoirs could be the contributing factors for transmission and acquisition of HEV infection. Investigation during health outreach is important to provide insights for future empirical research and implementation for improvement of lifestyle behaviours among the aborigines. Managing the risk of HEV infection in the aborigines may reduce the risk of HEV transmission to the local communities. © 2020 Blackwell Verlag GmbH
first_indexed 2024-03-06T06:03:40Z
format Article
id um.eprints-24759
institution Universiti Malaya
last_indexed 2024-03-06T06:03:40Z
publishDate 2020
publisher Wiley
record_format dspace
spelling um.eprints-247592020-06-10T00:25:24Z http://eprints.um.edu.my/24759/ The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia Wong, Li Ping Alias, Haridah Choy, Seow Huey Goh, Xiang Ting Lee, Soo Ching Lim, Yvonne Ai Lian Kee, Boon Pin Chua, Kek Heng Kamarulzaman, Adeeba Zheng, Zizheng Zhao, Qinjian Wu, Ting R Medicine Malaysia is a non-endemic country for hepatitis E virus (HEV) infection. However, seroprevalence as high as 50% among samples of aboriginal people were reported over two decades ago. A total of 207 samples collected from seven aboriginal villages in rural settlements across two states in Malaysia were analysed for anti-HEV IgG and IgM by an enzyme-linked immunoassay. Following the detection of anti-HEV seroprevalence, we organized health outreach to inform and educate the community. Qualitative interviews were conducted with individuals tested positive for anti-HEV antibodies. Data derived from interviews and observations were used to investigate possible lifestyle behaviours associated with HEV infection. Anti-HEV IgG was detected in six samples (5.9%) from the village of Dusun Kubur. Qualitative inquiry and observation study revealed poor dietary and household hygiene, contaminated food and water, contact with animal faeces, unsanitary and domestic waste disposal, and wildlife reservoirs could be the contributing factors for transmission and acquisition of HEV infection. Investigation during health outreach is important to provide insights for future empirical research and implementation for improvement of lifestyle behaviours among the aborigines. Managing the risk of HEV infection in the aborigines may reduce the risk of HEV transmission to the local communities. © 2020 Blackwell Verlag GmbH Wiley 2020 Article PeerReviewed Wong, Li Ping and Alias, Haridah and Choy, Seow Huey and Goh, Xiang Ting and Lee, Soo Ching and Lim, Yvonne Ai Lian and Kee, Boon Pin and Chua, Kek Heng and Kamarulzaman, Adeeba and Zheng, Zizheng and Zhao, Qinjian and Wu, Ting (2020) The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia. Zoonoses and Public Health, 67 (3). pp. 263-270. ISSN 1863-1959, DOI https://doi.org/10.1111/zph.12681 <https://doi.org/10.1111/zph.12681>. https://doi.org/10.1111/zph.12681 doi:10.1111/zph.12681
spellingShingle R Medicine
Wong, Li Ping
Alias, Haridah
Choy, Seow Huey
Goh, Xiang Ting
Lee, Soo Ching
Lim, Yvonne Ai Lian
Kee, Boon Pin
Chua, Kek Heng
Kamarulzaman, Adeeba
Zheng, Zizheng
Zhao, Qinjian
Wu, Ting
The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia
title The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia
title_full The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia
title_fullStr The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia
title_full_unstemmed The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia
title_short The study of seroprevalence of hepatitis E virus and an investigation into the lifestyle behaviours of the aborigines in Malaysia
title_sort study of seroprevalence of hepatitis e virus and an investigation into the lifestyle behaviours of the aborigines in malaysia
topic R Medicine
work_keys_str_mv AT wongliping thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT aliasharidah thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT choyseowhuey thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT gohxiangting thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT leesooching thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT limyvonneailian thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT keeboonpin thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT chuakekheng thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT kamarulzamanadeeba thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT zhengzizheng thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT zhaoqinjian thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT wuting thestudyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT wongliping studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT aliasharidah studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT choyseowhuey studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT gohxiangting studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT leesooching studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT limyvonneailian studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT keeboonpin studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT chuakekheng studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT kamarulzamanadeeba studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT zhengzizheng studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT zhaoqinjian studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia
AT wuting studyofseroprevalenceofhepatitisevirusandaninvestigationintothelifestylebehavioursoftheaboriginesinmalaysia