Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study
A case-controlled study was performed to evaluate taste and smell impairment, nausea or vomiting (NV) response to taste and smell and toleration to food texture, item and cooking method in hyperemesis gravidarum patients (HG) compared to gestation-matched controls from a university hospital and prim...
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| Format: | Article |
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Nature Research
2020
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| author | Tan, Peng Chiong Kartik, Balaraman Thanendran, Panjaratnam Zakaria, Rozita Win, Sandar Tin Omar, Siti Zawiah |
| author_facet | Tan, Peng Chiong Kartik, Balaraman Thanendran, Panjaratnam Zakaria, Rozita Win, Sandar Tin Omar, Siti Zawiah |
| author_sort | Tan, Peng Chiong |
| collection | UM |
| description | A case-controlled study was performed to evaluate taste and smell impairment, nausea or vomiting (NV) response to taste and smell and toleration to food texture, item and cooking method in hyperemesis gravidarum patients (HG) compared to gestation-matched controls from a university hospital and primary care clinic in Malaysia. Taste strips (4 base tastes), sniff sticks (16 selected smells) and a food-related questionnaire were used. 124 participants were recruited. Taste impairment was found in 13%(8/62) vs. 0%(0/62) P = 0.003 and the median for correct smell identification was 5[4–6] vs. 9[7–9] P < 0.001 in HG vs. controls. In HG, bitter was most likely (32%) and sweet taste least likely (5%) to provoke NV. In both arms, fish smell was most likely to provoke NV, 77% vs. 32% P < 0.001 and peppermint smell least likely 10% vs. 0% P = 0.012; NV response was significantly more likely for HG arm in 10/16 smells. In HG, worst and best NV responses to food-texture were pasty 69% and crunchy 26%; food-item, plain rice 71% and apple 16% and cooking-style, deep-frying 71% and steaming 55%. HG demonstrated taste and smell impairment and increased NV responses to many tastes and smells. Crunchy sweet uncooked food (apple or watermelon) maybe best tolerated in HG. © 2020, The Author(s). |
| first_indexed | 2024-03-06T06:03:53Z |
| format | Article |
| id | um.eprints-24826 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T06:03:53Z |
| publishDate | 2020 |
| publisher | Nature Research |
| record_format | dspace |
| spelling | um.eprints-248262020-06-15T03:16:11Z http://eprints.um.edu.my/24826/ Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study Tan, Peng Chiong Kartik, Balaraman Thanendran, Panjaratnam Zakaria, Rozita Win, Sandar Tin Omar, Siti Zawiah R Medicine A case-controlled study was performed to evaluate taste and smell impairment, nausea or vomiting (NV) response to taste and smell and toleration to food texture, item and cooking method in hyperemesis gravidarum patients (HG) compared to gestation-matched controls from a university hospital and primary care clinic in Malaysia. Taste strips (4 base tastes), sniff sticks (16 selected smells) and a food-related questionnaire were used. 124 participants were recruited. Taste impairment was found in 13%(8/62) vs. 0%(0/62) P = 0.003 and the median for correct smell identification was 5[4–6] vs. 9[7–9] P < 0.001 in HG vs. controls. In HG, bitter was most likely (32%) and sweet taste least likely (5%) to provoke NV. In both arms, fish smell was most likely to provoke NV, 77% vs. 32% P < 0.001 and peppermint smell least likely 10% vs. 0% P = 0.012; NV response was significantly more likely for HG arm in 10/16 smells. In HG, worst and best NV responses to food-texture were pasty 69% and crunchy 26%; food-item, plain rice 71% and apple 16% and cooking-style, deep-frying 71% and steaming 55%. HG demonstrated taste and smell impairment and increased NV responses to many tastes and smells. Crunchy sweet uncooked food (apple or watermelon) maybe best tolerated in HG. © 2020, The Author(s). Nature Research 2020 Article PeerReviewed Tan, Peng Chiong and Kartik, Balaraman and Thanendran, Panjaratnam and Zakaria, Rozita and Win, Sandar Tin and Omar, Siti Zawiah (2020) Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study. Scientific Reports, 10 (1). p. 4445. ISSN 2045-2322, DOI https://doi.org/10.1038/s41598-020-61114-y <https://doi.org/10.1038/s41598-020-61114-y>. https://doi.org/10.1038/s41598-020-61114-y doi:10.1038/s41598-020-61114-y |
| spellingShingle | R Medicine Tan, Peng Chiong Kartik, Balaraman Thanendran, Panjaratnam Zakaria, Rozita Win, Sandar Tin Omar, Siti Zawiah Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study |
| title | Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study |
| title_full | Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study |
| title_fullStr | Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study |
| title_full_unstemmed | Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study |
| title_short | Taste, smell and food-related nausea and vomiting responses in hyperemesis gravidarum: A case-controlled study |
| title_sort | taste smell and food related nausea and vomiting responses in hyperemesis gravidarum a case controlled study |
| topic | R Medicine |
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