Scar formation after skin injury to the human foetus in utero or the premature neonate

A macroscopically visible scar was present at birth in three infants with a history of injury during amniocentesis at 16–20 weeks’ gestation. In several neonates born between 21 and 31 weeks’ gestation, chemical injury to the skin caused by extravasation of calcium gluconate healed by formation of...

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Main Authors: Morrison, W.A., Hurley, J.V., Ahmad, T.S., Webster, H.R.
Format: Article
Language:English
Published: Elsevier 1999
Subjects:
Online Access:http://eprints.um.edu.my/2484/1/Scar_Formation.pdf
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author Morrison, W.A.
Hurley, J.V.
Ahmad, T.S.
Webster, H.R.
author_facet Morrison, W.A.
Hurley, J.V.
Ahmad, T.S.
Webster, H.R.
author_sort Morrison, W.A.
collection UM
description A macroscopically visible scar was present at birth in three infants with a history of injury during amniocentesis at 16–20 weeks’ gestation. In several neonates born between 21 and 31 weeks’ gestation, chemical injury to the skin caused by extravasation of calcium gluconate healed by formation of a large scar. In the infant born at 21 weeks, biopsy of the injured area showed infiltration by large numbers of neutrophils and macrophages. It appears that a very immature neonate can mount a prominent inflammatory reaction and that both a midtrimester foetus and a very immature neonate heal injuries to the skin by scar formation and not by scarless healing.
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spelling um.eprints-24842015-01-06T07:21:32Z http://eprints.um.edu.my/2484/ Scar formation after skin injury to the human foetus in utero or the premature neonate Morrison, W.A. Hurley, J.V. Ahmad, T.S. Webster, H.R. R Medicine A macroscopically visible scar was present at birth in three infants with a history of injury during amniocentesis at 16–20 weeks’ gestation. In several neonates born between 21 and 31 weeks’ gestation, chemical injury to the skin caused by extravasation of calcium gluconate healed by formation of a large scar. In the infant born at 21 weeks, biopsy of the injured area showed infiltration by large numbers of neutrophils and macrophages. It appears that a very immature neonate can mount a prominent inflammatory reaction and that both a midtrimester foetus and a very immature neonate heal injuries to the skin by scar formation and not by scarless healing. Elsevier 1999 Article PeerReviewed application/pdf en http://eprints.um.edu.my/2484/1/Scar_Formation.pdf Morrison, W.A. and Hurley, J.V. and Ahmad, T.S. and Webster, H.R. (1999) Scar formation after skin injury to the human foetus in utero or the premature neonate. British Journal of Plastic Surgery, 52 (1). pp. 6-11. ISSN 0007-1226, http://www.sciencedirect.com/science/article/pii/S0007122698930090
spellingShingle R Medicine
Morrison, W.A.
Hurley, J.V.
Ahmad, T.S.
Webster, H.R.
Scar formation after skin injury to the human foetus in utero or the premature neonate
title Scar formation after skin injury to the human foetus in utero or the premature neonate
title_full Scar formation after skin injury to the human foetus in utero or the premature neonate
title_fullStr Scar formation after skin injury to the human foetus in utero or the premature neonate
title_full_unstemmed Scar formation after skin injury to the human foetus in utero or the premature neonate
title_short Scar formation after skin injury to the human foetus in utero or the premature neonate
title_sort scar formation after skin injury to the human foetus in utero or the premature neonate
topic R Medicine
url http://eprints.um.edu.my/2484/1/Scar_Formation.pdf
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