Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity
Alpinia conchigera Griff. is a plant species from the family Zingiberaceae. Coloquially known as wild ginger, Alpinia conchigera Griff. is used as food condiment and for traditional treatment of skin diseases. Isolation studies to identify bioactive compounds of rhizomes of Alpinia conchigera yielde...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Published: |
Penerbit Universiti Sains Malaysia
2020
|
| Subjects: |
| _version_ | 1796962103408459776 |
|---|---|
| author | Mohamad Taib, Mohamad Nurul Azmi Anuar, Nursyazwani Mohd Hanafiah, Khayriyyah Al-Shammary, Aeman Ali Kudayr Saaid, Mardiana Awang, Khalijah |
| author_facet | Mohamad Taib, Mohamad Nurul Azmi Anuar, Nursyazwani Mohd Hanafiah, Khayriyyah Al-Shammary, Aeman Ali Kudayr Saaid, Mardiana Awang, Khalijah |
| author_sort | Mohamad Taib, Mohamad Nurul Azmi |
| collection | UM |
| description | Alpinia conchigera Griff. is a plant species from the family Zingiberaceae. Coloquially known as wild ginger, Alpinia conchigera Griff. is used as food condiment and for traditional treatment of skin diseases. Isolation studies to identify bioactive compounds of rhizomes of Alpinia conchigera yielded seven compounds; 1‘S-1'-acetoxychavicol acetate (1), trans-p-coumaryl diacetate (2), p-hydroxycinnamyl acetate (3), 1‘S-1'-hydroxychavicol acetate (4) p-hydroxybenzaldehyde (5), stigmasterol (6) and β-sitosterol (7). Compounds 1, 2 and 5 were evaluated for antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA). Among the compounds tested, Compound 1 showed good antimicrobial activity against the strain of MRSA with minimum inhibition concentration (MIC) value of 0.5 mg/mL. Meanwhile, Compounds 2 and 5 exhibited moderate activity with MIC value between 1.0 and 2.0 mg/mL. These findings indicate antimicrobial potential of 1‘S-1'- acetoxychavicol acetate (1), compound derived from rhizome of Alpinia conchigera Griff. against MRSA, which warrant further investigation. © Penerbit Universiti Sains Malaysia, 2020. |
| first_indexed | 2024-03-06T06:03:56Z |
| format | Article |
| id | um.eprints-24843 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T06:03:56Z |
| publishDate | 2020 |
| publisher | Penerbit Universiti Sains Malaysia |
| record_format | dspace |
| spelling | um.eprints-248432020-06-16T02:24:11Z http://eprints.um.edu.my/24843/ Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity Mohamad Taib, Mohamad Nurul Azmi Anuar, Nursyazwani Mohd Hanafiah, Khayriyyah Al-Shammary, Aeman Ali Kudayr Saaid, Mardiana Awang, Khalijah Q Science (General) QD Chemistry Alpinia conchigera Griff. is a plant species from the family Zingiberaceae. Coloquially known as wild ginger, Alpinia conchigera Griff. is used as food condiment and for traditional treatment of skin diseases. Isolation studies to identify bioactive compounds of rhizomes of Alpinia conchigera yielded seven compounds; 1‘S-1'-acetoxychavicol acetate (1), trans-p-coumaryl diacetate (2), p-hydroxycinnamyl acetate (3), 1‘S-1'-hydroxychavicol acetate (4) p-hydroxybenzaldehyde (5), stigmasterol (6) and β-sitosterol (7). Compounds 1, 2 and 5 were evaluated for antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA). Among the compounds tested, Compound 1 showed good antimicrobial activity against the strain of MRSA with minimum inhibition concentration (MIC) value of 0.5 mg/mL. Meanwhile, Compounds 2 and 5 exhibited moderate activity with MIC value between 1.0 and 2.0 mg/mL. These findings indicate antimicrobial potential of 1‘S-1'- acetoxychavicol acetate (1), compound derived from rhizome of Alpinia conchigera Griff. against MRSA, which warrant further investigation. © Penerbit Universiti Sains Malaysia, 2020. Penerbit Universiti Sains Malaysia 2020 Article PeerReviewed Mohamad Taib, Mohamad Nurul Azmi and Anuar, Nursyazwani and Mohd Hanafiah, Khayriyyah and Al-Shammary, Aeman Ali Kudayr and Saaid, Mardiana and Awang, Khalijah (2020) Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity. Tropical Life Sciences Research, 31 (1). pp. 159-178. ISSN 1985-3718, DOI https://doi.org/10.21315/tlsr2020.31.1.10 <https://doi.org/10.21315/tlsr2020.31.1.10>. https://doi.org/10.21315/tlsr2020.31.1.10 doi:10.21315/tlsr2020.31.1.10 |
| spellingShingle | Q Science (General) QD Chemistry Mohamad Taib, Mohamad Nurul Azmi Anuar, Nursyazwani Mohd Hanafiah, Khayriyyah Al-Shammary, Aeman Ali Kudayr Saaid, Mardiana Awang, Khalijah Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity |
| title | Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity |
| title_full | Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity |
| title_fullStr | Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity |
| title_full_unstemmed | Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity |
| title_short | Chemicals Constituents Isolated from Cultivate Alpinia conchigera Griff. and Antimicrobial Activity |
| title_sort | chemicals constituents isolated from cultivate alpinia conchigera griff and antimicrobial activity |
| topic | Q Science (General) QD Chemistry |
| work_keys_str_mv | AT mohamadtaibmohamadnurulazmi chemicalsconstituentsisolatedfromcultivatealpiniaconchigeragriffandantimicrobialactivity AT anuarnursyazwani chemicalsconstituentsisolatedfromcultivatealpiniaconchigeragriffandantimicrobialactivity AT mohdhanafiahkhayriyyah chemicalsconstituentsisolatedfromcultivatealpiniaconchigeragriffandantimicrobialactivity AT alshammaryaemanalikudayr chemicalsconstituentsisolatedfromcultivatealpiniaconchigeragriffandantimicrobialactivity AT saaidmardiana chemicalsconstituentsisolatedfromcultivatealpiniaconchigeragriffandantimicrobialactivity AT awangkhalijah chemicalsconstituentsisolatedfromcultivatealpiniaconchigeragriffandantimicrobialactivity |