Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain
This article illustrates a case of persistent trigeminal neuralgia in a medically compromised 65-year-old female who did not respond to pharmacotherapy. She had undergone several peripheral neurectomies as well as a failed right posterior fossa exploration that resulted in a cerebrospinal fluid leak...
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| Format: | Article |
| Language: | English |
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MOSBY-ELSEVIER, 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA
2010
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| Online Access: | http://eprints.um.edu.my/2842/1/Injection_of_botulinum_toxin_type_A_%28BOTOX%29_into_trigger_zone_of_trigeminal_neuralgia_as_a_means_to_control_pain.pdf |
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| author | Ngeow, Wei Cheong Nair, R. |
| author_facet | Ngeow, Wei Cheong Nair, R. |
| author_sort | Ngeow, Wei Cheong |
| collection | UM |
| description | This article illustrates a case of persistent trigeminal neuralgia in a medically compromised 65-year-old female who did not respond to pharmacotherapy. She had undergone several peripheral neurectomies as well as a failed right posterior fossa exploration that resulted in a cerebrospinal fluid leak. Persistent pain over the right external nasal area and right mental region was relieved for several hours after daily injections of bupivacaine. A trial of a single dose of 100 units of botulinum toxin type A (BOTOX) diluted in 2.5 mL saline was injected into the external nasal trigger zone (60 units) and to the mental nerve region (40 units). She achieved complete pain relief in the external nasal region for 5 months. Pain recurred and the site was again injected with 100 units of botulinum toxin type A (BOTOX). Pain relief at the mental region was partial. This was finally controlled with peripheral neurectomy. The patient was pain free with a maintenance dose of 200 mg carbamazepine daily for about 1 year, after which she elected to undergo stereotactic gamma knife radiosurgery when pain recurred at the external nasal region. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: e47-e50) |
| first_indexed | 2024-03-06T05:08:46Z |
| format | Article |
| id | um.eprints-2842 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:08:46Z |
| publishDate | 2010 |
| publisher | MOSBY-ELSEVIER, 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA |
| record_format | dspace |
| spelling | um.eprints-28422019-09-27T08:49:57Z http://eprints.um.edu.my/2842/ Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain Ngeow, Wei Cheong Nair, R. R Medicine RK Dentistry This article illustrates a case of persistent trigeminal neuralgia in a medically compromised 65-year-old female who did not respond to pharmacotherapy. She had undergone several peripheral neurectomies as well as a failed right posterior fossa exploration that resulted in a cerebrospinal fluid leak. Persistent pain over the right external nasal area and right mental region was relieved for several hours after daily injections of bupivacaine. A trial of a single dose of 100 units of botulinum toxin type A (BOTOX) diluted in 2.5 mL saline was injected into the external nasal trigger zone (60 units) and to the mental nerve region (40 units). She achieved complete pain relief in the external nasal region for 5 months. Pain recurred and the site was again injected with 100 units of botulinum toxin type A (BOTOX). Pain relief at the mental region was partial. This was finally controlled with peripheral neurectomy. The patient was pain free with a maintenance dose of 200 mg carbamazepine daily for about 1 year, after which she elected to undergo stereotactic gamma knife radiosurgery when pain recurred at the external nasal region. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: e47-e50) MOSBY-ELSEVIER, 360 PARK AVENUE SOUTH, NEW YORK, NY 10010-1710 USA 2010-03 Article PeerReviewed application/pdf en http://eprints.um.edu.my/2842/1/Injection_of_botulinum_toxin_type_A_%28BOTOX%29_into_trigger_zone_of_trigeminal_neuralgia_as_a_means_to_control_pain.pdf Ngeow, Wei Cheong and Nair, R. (2010) Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 109 (3). E47-E50. ISSN 1079-2104, DOI https://doi.org/10.1016/j.tripleo.2009.03.021 <https://doi.org/10.1016/j.tripleo.2009.03.021>. http://www.ncbi.nlm.nih.gov/pubmed/20219585 10.1016/j.tripleo.2009.03.021 |
| spellingShingle | R Medicine RK Dentistry Ngeow, Wei Cheong Nair, R. Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain |
| title | Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain |
| title_full | Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain |
| title_fullStr | Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain |
| title_full_unstemmed | Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain |
| title_short | Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain |
| title_sort | injection of botulinum toxin type a botox into trigger zone of trigeminal neuralgia as a means to control pain |
| topic | R Medicine RK Dentistry |
| url | http://eprints.um.edu.my/2842/1/Injection_of_botulinum_toxin_type_A_%28BOTOX%29_into_trigger_zone_of_trigeminal_neuralgia_as_a_means_to_control_pain.pdf |
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