The efficacy of Gelam Honey dressing towards excisional wound healing

Honey is one of the oldest substances used in wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group, Intrasite Gel group, and Gelam honey group) with 2 cm by 2 ...

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Main Authors: Tan, Mui Koon, Hasan Adli, Durriyyah Sharifah, Tumiran, Mohd Amzari, Abdulla, Mahmood Ameen, Yusoff, Kamaruddin Mohd
Format: Article
Language:English
Published: Hindawi 2012
Subjects:
Online Access:http://eprints.um.edu.my/3167/1/1.pdf
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author Tan, Mui Koon
Hasan Adli, Durriyyah Sharifah
Tumiran, Mohd Amzari
Abdulla, Mahmood Ameen
Yusoff, Kamaruddin Mohd
author_facet Tan, Mui Koon
Hasan Adli, Durriyyah Sharifah
Tumiran, Mohd Amzari
Abdulla, Mahmood Ameen
Yusoff, Kamaruddin Mohd
author_sort Tan, Mui Koon
collection UM
description Honey is one of the oldest substances used in wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group, Intrasite Gel group, and Gelam honey group) with 2 cm by 2 cm full thickness, excisional wound created on neck area. Wounds were dressed topically according to groups. Rats were sacrificed on days 1, 5, 10, and 15 of treatments. Wounds were then processed for macroscopic and histological observations. Gelam-honey-dressed wounds healed earlier (day 13) than untreated and saline treated groups, as did wounds treated with Intrasite Gel. Honey-treated wounds exhibited less scab and only thin scar formations. Histological features demonstrated positive effects of Gelam honey on the wounds. This paper showed that Gelam honey dressing on excisional wound accelerated the process of wound healing.
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spelling um.eprints-31672020-01-29T06:09:52Z http://eprints.um.edu.my/3167/ The efficacy of Gelam Honey dressing towards excisional wound healing Tan, Mui Koon Hasan Adli, Durriyyah Sharifah Tumiran, Mohd Amzari Abdulla, Mahmood Ameen Yusoff, Kamaruddin Mohd R Medicine Honey is one of the oldest substances used in wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group, Intrasite Gel group, and Gelam honey group) with 2 cm by 2 cm full thickness, excisional wound created on neck area. Wounds were dressed topically according to groups. Rats were sacrificed on days 1, 5, 10, and 15 of treatments. Wounds were then processed for macroscopic and histological observations. Gelam-honey-dressed wounds healed earlier (day 13) than untreated and saline treated groups, as did wounds treated with Intrasite Gel. Honey-treated wounds exhibited less scab and only thin scar formations. Histological features demonstrated positive effects of Gelam honey on the wounds. This paper showed that Gelam honey dressing on excisional wound accelerated the process of wound healing. Hindawi 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/3167/1/1.pdf Tan, Mui Koon and Hasan Adli, Durriyyah Sharifah and Tumiran, Mohd Amzari and Abdulla, Mahmood Ameen and Yusoff, Kamaruddin Mohd (2012) The efficacy of Gelam Honey dressing towards excisional wound healing. Evidence-Based Complementary and Alternative Medicine, 2012. p. 805932. ISSN 1741-427X, DOI https://doi.org/10.1155/2012/805932 <https://doi.org/10.1155/2012/805932>. https://doi.org/10.1155/2012/805932 doi:10.1155/2012/805932
spellingShingle R Medicine
Tan, Mui Koon
Hasan Adli, Durriyyah Sharifah
Tumiran, Mohd Amzari
Abdulla, Mahmood Ameen
Yusoff, Kamaruddin Mohd
The efficacy of Gelam Honey dressing towards excisional wound healing
title The efficacy of Gelam Honey dressing towards excisional wound healing
title_full The efficacy of Gelam Honey dressing towards excisional wound healing
title_fullStr The efficacy of Gelam Honey dressing towards excisional wound healing
title_full_unstemmed The efficacy of Gelam Honey dressing towards excisional wound healing
title_short The efficacy of Gelam Honey dressing towards excisional wound healing
title_sort efficacy of gelam honey dressing towards excisional wound healing
topic R Medicine
url http://eprints.um.edu.my/3167/1/1.pdf
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