Toxoplasmosis: prevalence and risk factors
The gene encoding the excretory-secretory antigen TES-120 of dog ascarid worm Toxocara canis was cloned into the bacterium Escherichia coli. The specificity of the recombinant TES- 120 antigen produced by the bacterium was investigated.A total of 45 human serum samples from patients infected with di...
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Informa Healthcare
2003
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author | Nissapatorn, V. Noor Azmi, M.A. Cho, S.M. Fong, Mun Yik Ithoi, Init Rohela, M. Khairul Anuar, A. Quek, K.F. Latt, H.M. |
author_facet | Nissapatorn, V. Noor Azmi, M.A. Cho, S.M. Fong, Mun Yik Ithoi, Init Rohela, M. Khairul Anuar, A. Quek, K.F. Latt, H.M. |
author_sort | Nissapatorn, V. |
collection | UM |
description | The gene encoding the excretory-secretory antigen TES-120 of dog ascarid worm Toxocara canis was cloned into the bacterium Escherichia coli. The specificity of the recombinant TES- 120 antigen produced by the bacterium was investigated.A total of 45 human serum samples from patients infected with different helminthes and protozoa, including 8 cases of toxocariasis, were tested against the recombinant antigens in immunoblot assays. The results from the assays revealed that the recombinant TES-120 antigen reacted with sera from toxocariasis patients only. This highly specific recombinant TES-120 antigen can potentially be used for the development of an inexpensive serodiagnostic assay for human toxocariasis. |
first_indexed | 2024-03-06T05:09:33Z |
format | Article |
id | um.eprints-3272 |
institution | Universiti Malaya |
last_indexed | 2024-03-06T05:09:33Z |
publishDate | 2003 |
publisher | Informa Healthcare |
record_format | dspace |
spelling | um.eprints-32722021-12-30T08:40:24Z http://eprints.um.edu.my/3272/ Toxoplasmosis: prevalence and risk factors Nissapatorn, V. Noor Azmi, M.A. Cho, S.M. Fong, Mun Yik Ithoi, Init Rohela, M. Khairul Anuar, A. Quek, K.F. Latt, H.M. R Medicine The gene encoding the excretory-secretory antigen TES-120 of dog ascarid worm Toxocara canis was cloned into the bacterium Escherichia coli. The specificity of the recombinant TES- 120 antigen produced by the bacterium was investigated.A total of 45 human serum samples from patients infected with different helminthes and protozoa, including 8 cases of toxocariasis, were tested against the recombinant antigens in immunoblot assays. The results from the assays revealed that the recombinant TES-120 antigen reacted with sera from toxocariasis patients only. This highly specific recombinant TES-120 antigen can potentially be used for the development of an inexpensive serodiagnostic assay for human toxocariasis. Informa Healthcare 2003 Article PeerReviewed Nissapatorn, V. and Noor Azmi, M.A. and Cho, S.M. and Fong, Mun Yik and Ithoi, Init and Rohela, M. and Khairul Anuar, A. and Quek, K.F. and Latt, H.M. (2003) Toxoplasmosis: prevalence and risk factors. Journal of Obstetrics and Gynaecology, 23 (6). pp. 618-624. ISSN 0144-3615, DOI https://doi.org/10.1080/01443610310001604376 <https://doi.org/10.1080/01443610310001604376>. https://doi.org/10.1080/01443610310001604376 doi:10.1080/01443610310001604376 |
spellingShingle | R Medicine Nissapatorn, V. Noor Azmi, M.A. Cho, S.M. Fong, Mun Yik Ithoi, Init Rohela, M. Khairul Anuar, A. Quek, K.F. Latt, H.M. Toxoplasmosis: prevalence and risk factors |
title | Toxoplasmosis: prevalence and risk factors |
title_full | Toxoplasmosis: prevalence and risk factors |
title_fullStr | Toxoplasmosis: prevalence and risk factors |
title_full_unstemmed | Toxoplasmosis: prevalence and risk factors |
title_short | Toxoplasmosis: prevalence and risk factors |
title_sort | toxoplasmosis prevalence and risk factors |
topic | R Medicine |
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