Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin
In view of the controversy with respect to the interaction of jacalin with human IgA2, a study was undertaken to assess the reactivity of the Artocarpus heterophyllus lectin, as well as the lectin from Artocarpus integer (lectin C), with subclasses of human immunoglobulin A by ELISA. Our data is con...
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| Format: | Article |
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1992
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| author | Hashim, Onn Haji Kobayashi, K. Taniguchi, N. |
| author_facet | Hashim, Onn Haji Kobayashi, K. Taniguchi, N. |
| author_sort | Hashim, Onn Haji |
| collection | UM |
| description | In view of the controversy with respect to the interaction of jacalin with human IgA2, a study was undertaken to assess the reactivity of the Artocarpus heterophyllus lectin, as well as the lectin from Artocarpus integer (lectin C), with subclasses of human immunoglobulin A by ELISA. Our data is consistent with the view that Artocarpus lectins have no affinity for the IgA2 immunoglobulins. In further support of the findings, we have established that N-linked oligosaccharide moieties of IgA have no significant bearing in the lectin-immunoglobulin binding. Interaction was also not affected in the presence of 1 (w/v) BSA. |
| first_indexed | 2024-03-06T05:09:57Z |
| format | Article |
| id | um.eprints-3452 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:09:57Z |
| publishDate | 1992 |
| record_format | dspace |
| spelling | um.eprints-34522019-10-24T08:19:36Z http://eprints.um.edu.my/3452/ Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin Hashim, Onn Haji Kobayashi, K. Taniguchi, N. R Medicine In view of the controversy with respect to the interaction of jacalin with human IgA2, a study was undertaken to assess the reactivity of the Artocarpus heterophyllus lectin, as well as the lectin from Artocarpus integer (lectin C), with subclasses of human immunoglobulin A by ELISA. Our data is consistent with the view that Artocarpus lectins have no affinity for the IgA2 immunoglobulins. In further support of the findings, we have established that N-linked oligosaccharide moieties of IgA have no significant bearing in the lectin-immunoglobulin binding. Interaction was also not affected in the presence of 1 (w/v) BSA. 1992 Article PeerReviewed Hashim, Onn Haji and Kobayashi, K. and Taniguchi, N. (1992) Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin. Biochemistry International, 27 (3). pp. 423-429. ISSN 0158-5231, |
| spellingShingle | R Medicine Hashim, Onn Haji Kobayashi, K. Taniguchi, N. Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin |
| title | Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin |
| title_full | Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin |
| title_fullStr | Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin |
| title_full_unstemmed | Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin |
| title_short | Interaction of artocarpus lectins with human-iga does not involve asparagine-linked oligosaccharide of the immunoglobulin |
| title_sort | interaction of artocarpus lectins with human iga does not involve asparagine linked oligosaccharide of the immunoglobulin |
| topic | R Medicine |
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