Genetic variability of Blastocystis sp isolates obtained from cancer and HIV/AIDS patients

This represents the first study to determine the genetic diversity of Blastocystis sp. among cancer and HIV/AIDS patients. Forty Blastocystis sp. isolates obtained from 20 cancer and 20 HIV/AIDS patients were genotyped by PCR using seven pairs of known sequenced-tagged site primers. Out of the 40 is...

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Bibliographic Details
Main Authors: Tan, T.C., Ong, S.C., Suresh, K.G.
Format: Article
Language:English
Published: 2009
Subjects:
Online Access:http://eprints.um.edu.my/4027/1/Tan-2009-Genetic_variability.pdf
Description
Summary:This represents the first study to determine the genetic diversity of Blastocystis sp. among cancer and HIV/AIDS patients. Forty Blastocystis sp. isolates obtained from 20 cancer and 20 HIV/AIDS patients were genotyped by PCR using seven pairs of known sequenced-tagged site primers. Out of the 40 isolates, 38 were identified as one of the known genotypes and two isolates were negative with all the STS primers. Blastocystis sp. subtype 3 which is reported to be associated with disease was found to be predominant among the study subjects.