Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia
This study aims to evaluate the current seroprevalence of toxoplasmosis among indigenous communities in Peninsular Malaysia and relate its association with epidemiological data. Overall seroprevalence of Toxoplasma gondii was 37.0 with 31.0 immunoglobulin (Ig) G, 1.8 IgM, and 4.2 seropositivity for...
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| Format: | Article |
| Language: | English |
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2011
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| Online Access: | http://eprints.um.edu.my/4066/1/Ngui-2011-Seroprevalence_and_S.pdf |
| _version_ | 1825718892491702272 |
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| author | Ngui, R. Lim, Y.A.L. Amir, N.F.H. Nissapatorn, V. Mahmud, R. |
| author_facet | Ngui, R. Lim, Y.A.L. Amir, N.F.H. Nissapatorn, V. Mahmud, R. |
| author_sort | Ngui, R. |
| collection | UM |
| description | This study aims to evaluate the current seroprevalence of toxoplasmosis among indigenous communities in Peninsular Malaysia and relate its association with epidemiological data. Overall seroprevalence of Toxoplasma gondii was 37.0 with 31.0 immunoglobulin (Ig) G, 1.8 IgM, and 4.2 seropositivity for both anti-Toxoplasma antibodies. Multivariate analysis showed that age above 12 years (odds ratio OR = 2.70, 95% confidence interval CI = 1.75-4.04, P < 0.001), using untreated river and mountain water supplies (OR = 1.50,95% CI = 1.01-2.40, P = 0.050), and close proximity with cats (OR = 1.40, 95% CI = 1.10-1.76, P = 0.010) were factors associated with toxoplasmosis. Given the high seroprevalence of toxoplasmosis among these communities who live in poor socioeconomic conditions, a comprehensive health surveillance program and screening should be initiated among women of childbearing age and pregnant women during the antenatal period for early diagnosis and treatment. The role of domestic cats and environmental contamination with oocyst in soil and water has to be highlighted and addressed in future prevention strategies for these communities. |
| first_indexed | 2024-03-06T05:11:15Z |
| format | Article |
| id | um.eprints-4066 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:11:15Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | um.eprints-40662012-11-07T03:46:58Z http://eprints.um.edu.my/4066/ Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia Ngui, R. Lim, Y.A.L. Amir, N.F.H. Nissapatorn, V. Mahmud, R. R Medicine This study aims to evaluate the current seroprevalence of toxoplasmosis among indigenous communities in Peninsular Malaysia and relate its association with epidemiological data. Overall seroprevalence of Toxoplasma gondii was 37.0 with 31.0 immunoglobulin (Ig) G, 1.8 IgM, and 4.2 seropositivity for both anti-Toxoplasma antibodies. Multivariate analysis showed that age above 12 years (odds ratio OR = 2.70, 95% confidence interval CI = 1.75-4.04, P < 0.001), using untreated river and mountain water supplies (OR = 1.50,95% CI = 1.01-2.40, P = 0.050), and close proximity with cats (OR = 1.40, 95% CI = 1.10-1.76, P = 0.010) were factors associated with toxoplasmosis. Given the high seroprevalence of toxoplasmosis among these communities who live in poor socioeconomic conditions, a comprehensive health surveillance program and screening should be initiated among women of childbearing age and pregnant women during the antenatal period for early diagnosis and treatment. The role of domestic cats and environmental contamination with oocyst in soil and water has to be highlighted and addressed in future prevention strategies for these communities. 2011 Article PeerReviewed application/pdf en http://eprints.um.edu.my/4066/1/Ngui-2011-Seroprevalence_and_S.pdf Ngui, R. and Lim, Y.A.L. and Amir, N.F.H. and Nissapatorn, V. and Mahmud, R. (2011) Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia. American Journal of Tropical Medicine and Hygiene, 85 (4). pp. 660-666. ISSN 0002-9637, DOI 21976569. http://www.ncbi.nlm.nih.gov/pubmed/21976569 21976569 |
| spellingShingle | R Medicine Ngui, R. Lim, Y.A.L. Amir, N.F.H. Nissapatorn, V. Mahmud, R. Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia |
| title | Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia |
| title_full | Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia |
| title_fullStr | Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia |
| title_full_unstemmed | Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia |
| title_short | Seroprevalence and sources of toxoplasmosis among Orang Asli (Indigenous) communities in Peninsular Malaysia |
| title_sort | seroprevalence and sources of toxoplasmosis among orang asli indigenous communities in peninsular malaysia |
| topic | R Medicine |
| url | http://eprints.um.edu.my/4066/1/Ngui-2011-Seroprevalence_and_S.pdf |
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