Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions
Early detection of oral potentially malignant epithelial lesions (PMELs) is aimed at improving survival rates as carcinogenesis is a multistep process and prevention is possible if these lesions are detected at an early and reversible stage of the disease. A prospective clinical study aimed at deter...
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| Format: | Article |
| Language: | English English |
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Springer
2012
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| Online Access: | http://eprints.um.edu.my/4326/2/Prevalence_of_bilateral_%27mirror-image%27_lesions_in_patients_with_oral_potentially_malignant_epithelial_lesions.pdf http://eprints.um.edu.my/4326/1/Prevalence_of_bilateral_%27mirror-image%27_lesions_in_patients_with_oral_potentially_malignant_epithelial_lesions.pdf |
| _version_ | 1825718926929035264 |
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| author | Siar, Chong Huat Mah, Michelle Clare Gill, Praveen Preet |
| author_facet | Siar, Chong Huat Mah, Michelle Clare Gill, Praveen Preet |
| author_sort | Siar, Chong Huat |
| collection | UM |
| description | Early detection of oral potentially malignant epithelial lesions (PMELs) is aimed at improving survival rates as carcinogenesis is a multistep process and prevention is possible if these lesions are detected at an early and reversible stage of the disease. A prospective clinical study aimed at determining the prevalence of bilateral 'mirror-image' oral PMELs was carried out. Sample consisted of 32 (53.3) Indians, 23 (38.3) Chinese, 4 (6.7) Malays and one (1.7) Nepalese. All had histopathological confirmation of their primary existing PMEL as inclusion criteria. A total of 70 primary lesions were detected. The most common PMEL found was oral lichen planus. Of these, 28 (46.7) patients exhibited bilateral 'mirror-image' lesions (n = 42) either synchronously (n = 32/42) or metachronously (n = 10/42). The remaining 32 (53.3) patients had normal-looking contralateral mucosa. Present findings suggest that patients presenting with oral PMELs are at greater risk of developing a second lesion, most probably in the contralateral 'mirror-image' site. |
| first_indexed | 2024-03-06T05:11:45Z |
| format | Article |
| id | um.eprints-4326 |
| institution | Universiti Malaya |
| language | English English |
| last_indexed | 2024-03-06T05:11:45Z |
| publishDate | 2012 |
| publisher | Springer |
| record_format | dspace |
| spelling | um.eprints-43262019-11-22T04:16:33Z http://eprints.um.edu.my/4326/ Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions Siar, Chong Huat Mah, Michelle Clare Gill, Praveen Preet RK Dentistry Early detection of oral potentially malignant epithelial lesions (PMELs) is aimed at improving survival rates as carcinogenesis is a multistep process and prevention is possible if these lesions are detected at an early and reversible stage of the disease. A prospective clinical study aimed at determining the prevalence of bilateral 'mirror-image' oral PMELs was carried out. Sample consisted of 32 (53.3) Indians, 23 (38.3) Chinese, 4 (6.7) Malays and one (1.7) Nepalese. All had histopathological confirmation of their primary existing PMEL as inclusion criteria. A total of 70 primary lesions were detected. The most common PMEL found was oral lichen planus. Of these, 28 (46.7) patients exhibited bilateral 'mirror-image' lesions (n = 42) either synchronously (n = 32/42) or metachronously (n = 10/42). The remaining 32 (53.3) patients had normal-looking contralateral mucosa. Present findings suggest that patients presenting with oral PMELs are at greater risk of developing a second lesion, most probably in the contralateral 'mirror-image' site. Springer 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/4326/2/Prevalence_of_bilateral_%27mirror-image%27_lesions_in_patients_with_oral_potentially_malignant_epithelial_lesions.pdf application/pdf en http://eprints.um.edu.my/4326/1/Prevalence_of_bilateral_%27mirror-image%27_lesions_in_patients_with_oral_potentially_malignant_epithelial_lesions.pdf Siar, Chong Huat and Mah, Michelle Clare and Gill, Praveen Preet (2012) Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions. European Archives of Oto-Rhino-Laryngology, 269 (3). pp. 999-1004. ISSN 0937-4477, DOI https://doi.org/10.1007/s00405-011-1712-x <https://doi.org/10.1007/s00405-011-1712-x>. https://doi.org/10.1007/s00405-011-1712-x doi:10.1007/s00405-011-1712-x |
| spellingShingle | RK Dentistry Siar, Chong Huat Mah, Michelle Clare Gill, Praveen Preet Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions |
| title | Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions |
| title_full | Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions |
| title_fullStr | Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions |
| title_full_unstemmed | Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions |
| title_short | Prevalence of bilateral 'mirror-image' lesions in patients with oral potentially malignant epithelial lesions |
| title_sort | prevalence of bilateral mirror image lesions in patients with oral potentially malignant epithelial lesions |
| topic | RK Dentistry |
| url | http://eprints.um.edu.my/4326/2/Prevalence_of_bilateral_%27mirror-image%27_lesions_in_patients_with_oral_potentially_malignant_epithelial_lesions.pdf http://eprints.um.edu.my/4326/1/Prevalence_of_bilateral_%27mirror-image%27_lesions_in_patients_with_oral_potentially_malignant_epithelial_lesions.pdf |
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