Periodontal response to two intracanal medicaments in replanted monkey incisors

Intracanal medicaments are recommended for use in replanted teeth to inhibit inflammatory root resorption. This study compared the effect of calcium hydroxide (Pulpdent (R)) and a corticosteroid-antibiotic paste (Ledermix (R)) on periodontal healing and root resorption following replantation. Inciso...

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Main Authors: Thong, Y.L., Messer, H.H., Siar, C.H., Saw, L.H.
Format: Article
Language:English
Published: 2001
Subjects:
Online Access:http://eprints.um.edu.my/4345/1/Periodontal_response_to_two_intracanal_medicaments_in_replanted_monkey_incisors.pdf
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author Thong, Y.L.
Messer, H.H.
Siar, C.H.
Saw, L.H.
author_facet Thong, Y.L.
Messer, H.H.
Siar, C.H.
Saw, L.H.
author_sort Thong, Y.L.
collection UM
description Intracanal medicaments are recommended for use in replanted teeth to inhibit inflammatory root resorption. This study compared the effect of calcium hydroxide (Pulpdent (R)) and a corticosteroid-antibiotic paste (Ledermix (R)) on periodontal healing and root resorption following replantation. Incisors of eight Macaca fascicularis monkeys were extracted, stored dry for 15 min and replanted. After I I days, root canals in two adjacent maxillary incisors were treated with one medicament and contralateral incisors with the other medicament, or left as untreated controls. Animals were sacrificed 8 weeks later and the teeth prepared for histomorphometric evaluation of periodontal ligament inflammation and root resorption. Periodontal ligament inflammation and inflammatory root resorption were markedly inhibited by both calcium hydroxide and corticosteroid-antibiotic relative to untreated controls. Replacement resorption was lowest in the corticosteroid-antibiotic group, and significantly (P <0.05) more normal periodontal ligament was present in this group (79.6) than in calcium hydroxide and control groups (64.6 and 62.7, respectively). Treatment with the corticosteroid-antibiotic inhibited inflammatory resorption and was slightly more effective than calcium hydroxide in producing a periodontal healing response.
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spelling um.eprints-43452013-01-10T00:41:30Z http://eprints.um.edu.my/4345/ Periodontal response to two intracanal medicaments in replanted monkey incisors Thong, Y.L. Messer, H.H. Siar, C.H. Saw, L.H. RK Dentistry Intracanal medicaments are recommended for use in replanted teeth to inhibit inflammatory root resorption. This study compared the effect of calcium hydroxide (Pulpdent (R)) and a corticosteroid-antibiotic paste (Ledermix (R)) on periodontal healing and root resorption following replantation. Incisors of eight Macaca fascicularis monkeys were extracted, stored dry for 15 min and replanted. After I I days, root canals in two adjacent maxillary incisors were treated with one medicament and contralateral incisors with the other medicament, or left as untreated controls. Animals were sacrificed 8 weeks later and the teeth prepared for histomorphometric evaluation of periodontal ligament inflammation and root resorption. Periodontal ligament inflammation and inflammatory root resorption were markedly inhibited by both calcium hydroxide and corticosteroid-antibiotic relative to untreated controls. Replacement resorption was lowest in the corticosteroid-antibiotic group, and significantly (P <0.05) more normal periodontal ligament was present in this group (79.6) than in calcium hydroxide and control groups (64.6 and 62.7, respectively). Treatment with the corticosteroid-antibiotic inhibited inflammatory resorption and was slightly more effective than calcium hydroxide in producing a periodontal healing response. 2001 Article PeerReviewed application/pdf en http://eprints.um.edu.my/4345/1/Periodontal_response_to_two_intracanal_medicaments_in_replanted_monkey_incisors.pdf Thong, Y.L. and Messer, H.H. and Siar, C.H. and Saw, L.H. (2001) Periodontal response to two intracanal medicaments in replanted monkey incisors. Dental Traumatology, 17 (6). pp. 254-259. ISSN 1600-4469, DOI https://doi.org/10.1034/j.1600-9657.2001.170603.x <https://doi.org/10.1034/j.1600-9657.2001.170603.x>. 10.1034/j.1600-9657.2001.170603.x
spellingShingle RK Dentistry
Thong, Y.L.
Messer, H.H.
Siar, C.H.
Saw, L.H.
Periodontal response to two intracanal medicaments in replanted monkey incisors
title Periodontal response to two intracanal medicaments in replanted monkey incisors
title_full Periodontal response to two intracanal medicaments in replanted monkey incisors
title_fullStr Periodontal response to two intracanal medicaments in replanted monkey incisors
title_full_unstemmed Periodontal response to two intracanal medicaments in replanted monkey incisors
title_short Periodontal response to two intracanal medicaments in replanted monkey incisors
title_sort periodontal response to two intracanal medicaments in replanted monkey incisors
topic RK Dentistry
url http://eprints.um.edu.my/4345/1/Periodontal_response_to_two_intracanal_medicaments_in_replanted_monkey_incisors.pdf
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AT sawlh periodontalresponsetotwointracanalmedicamentsinreplantedmonkeyincisors