Periodontal response to two intracanal medicaments in replanted monkey incisors
Intracanal medicaments are recommended for use in replanted teeth to inhibit inflammatory root resorption. This study compared the effect of calcium hydroxide (Pulpdent (R)) and a corticosteroid-antibiotic paste (Ledermix (R)) on periodontal healing and root resorption following replantation. Inciso...
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Format: | Article |
Language: | English |
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2001
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Online Access: | http://eprints.um.edu.my/4345/1/Periodontal_response_to_two_intracanal_medicaments_in_replanted_monkey_incisors.pdf |
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author | Thong, Y.L. Messer, H.H. Siar, C.H. Saw, L.H. |
author_facet | Thong, Y.L. Messer, H.H. Siar, C.H. Saw, L.H. |
author_sort | Thong, Y.L. |
collection | UM |
description | Intracanal medicaments are recommended for use in replanted teeth to inhibit inflammatory root resorption. This study compared the effect of calcium hydroxide (Pulpdent (R)) and a corticosteroid-antibiotic paste (Ledermix (R)) on periodontal healing and root resorption following replantation. Incisors of eight Macaca fascicularis monkeys were extracted, stored dry for 15 min and replanted. After I I days, root canals in two adjacent maxillary incisors were treated with one medicament and contralateral incisors with the other medicament, or left as untreated controls. Animals were sacrificed 8 weeks later and the teeth prepared for histomorphometric evaluation of periodontal ligament inflammation and root resorption. Periodontal ligament inflammation and inflammatory root resorption were markedly inhibited by both calcium hydroxide and corticosteroid-antibiotic relative to untreated controls. Replacement resorption was lowest in the corticosteroid-antibiotic group, and significantly (P <0.05) more normal periodontal ligament was present in this group (79.6) than in calcium hydroxide and control groups (64.6 and 62.7, respectively). Treatment with the corticosteroid-antibiotic inhibited inflammatory resorption and was slightly more effective than calcium hydroxide in producing a periodontal healing response. |
first_indexed | 2024-03-06T05:11:48Z |
format | Article |
id | um.eprints-4345 |
institution | Universiti Malaya |
language | English |
last_indexed | 2024-03-06T05:11:48Z |
publishDate | 2001 |
record_format | dspace |
spelling | um.eprints-43452013-01-10T00:41:30Z http://eprints.um.edu.my/4345/ Periodontal response to two intracanal medicaments in replanted monkey incisors Thong, Y.L. Messer, H.H. Siar, C.H. Saw, L.H. RK Dentistry Intracanal medicaments are recommended for use in replanted teeth to inhibit inflammatory root resorption. This study compared the effect of calcium hydroxide (Pulpdent (R)) and a corticosteroid-antibiotic paste (Ledermix (R)) on periodontal healing and root resorption following replantation. Incisors of eight Macaca fascicularis monkeys were extracted, stored dry for 15 min and replanted. After I I days, root canals in two adjacent maxillary incisors were treated with one medicament and contralateral incisors with the other medicament, or left as untreated controls. Animals were sacrificed 8 weeks later and the teeth prepared for histomorphometric evaluation of periodontal ligament inflammation and root resorption. Periodontal ligament inflammation and inflammatory root resorption were markedly inhibited by both calcium hydroxide and corticosteroid-antibiotic relative to untreated controls. Replacement resorption was lowest in the corticosteroid-antibiotic group, and significantly (P <0.05) more normal periodontal ligament was present in this group (79.6) than in calcium hydroxide and control groups (64.6 and 62.7, respectively). Treatment with the corticosteroid-antibiotic inhibited inflammatory resorption and was slightly more effective than calcium hydroxide in producing a periodontal healing response. 2001 Article PeerReviewed application/pdf en http://eprints.um.edu.my/4345/1/Periodontal_response_to_two_intracanal_medicaments_in_replanted_monkey_incisors.pdf Thong, Y.L. and Messer, H.H. and Siar, C.H. and Saw, L.H. (2001) Periodontal response to two intracanal medicaments in replanted monkey incisors. Dental Traumatology, 17 (6). pp. 254-259. ISSN 1600-4469, DOI https://doi.org/10.1034/j.1600-9657.2001.170603.x <https://doi.org/10.1034/j.1600-9657.2001.170603.x>. 10.1034/j.1600-9657.2001.170603.x |
spellingShingle | RK Dentistry Thong, Y.L. Messer, H.H. Siar, C.H. Saw, L.H. Periodontal response to two intracanal medicaments in replanted monkey incisors |
title | Periodontal response to two intracanal medicaments in replanted monkey incisors |
title_full | Periodontal response to two intracanal medicaments in replanted monkey incisors |
title_fullStr | Periodontal response to two intracanal medicaments in replanted monkey incisors |
title_full_unstemmed | Periodontal response to two intracanal medicaments in replanted monkey incisors |
title_short | Periodontal response to two intracanal medicaments in replanted monkey incisors |
title_sort | periodontal response to two intracanal medicaments in replanted monkey incisors |
topic | RK Dentistry |
url | http://eprints.um.edu.my/4345/1/Periodontal_response_to_two_intracanal_medicaments_in_replanted_monkey_incisors.pdf |
work_keys_str_mv | AT thongyl periodontalresponsetotwointracanalmedicamentsinreplantedmonkeyincisors AT messerhh periodontalresponsetotwointracanalmedicamentsinreplantedmonkeyincisors AT siarch periodontalresponsetotwointracanalmedicamentsinreplantedmonkeyincisors AT sawlh periodontalresponsetotwointracanalmedicamentsinreplantedmonkeyincisors |