Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase.
We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing ana...
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| Format: | Article |
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American Society for Microbiology
2002
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| _version_ | 1796944635781709824 |
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| author | Ho, Siaw Eng Subramaniam, Geetha Palasubramaniam, Selvi Navaratnam, Parasakthi |
| author_facet | Ho, Siaw Eng Subramaniam, Geetha Palasubramaniam, Selvi Navaratnam, Parasakthi |
| author_sort | Ho, Siaw Eng |
| collection | UM |
| description | We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant. |
| first_indexed | 2024-03-06T05:04:43Z |
| format | Article |
| id | um.eprints-452 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:04:43Z |
| publishDate | 2002 |
| publisher | American Society for Microbiology |
| record_format | dspace |
| spelling | um.eprints-4522019-02-07T07:15:15Z http://eprints.um.edu.my/452/ Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. Ho, Siaw Eng Subramaniam, Geetha Palasubramaniam, Selvi Navaratnam, Parasakthi R Medicine (General) We have isolated and identified a carbapenem-resistant Pseudomonas aeruginosa strain from Malaysia that produces an IMP-7 metallo-beta-lactamase. This isolate showed high-level resistance to meropenem and imipenem, the MICs of which were 256 and 128 micro g/ml, respectively. Isoelectric focusing analyses revealed pI values of >9.0, 8.2, and 7.8, which indicated the possible presence of IMP and OXA. DNA sequencing confirmed the identity of the IMP-7 determinant. American Society for Microbiology 2002-10 Article PeerReviewed Ho, Siaw Eng and Subramaniam, Geetha and Palasubramaniam, Selvi and Navaratnam, Parasakthi (2002) Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. Antimicrobial Agents and Chemotherapy, 46 (10). pp. 3286-7. ISSN 0066-4804, DOI 12234862. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC128803/?tool=pubmed 12234862 |
| spellingShingle | R Medicine (General) Ho, Siaw Eng Subramaniam, Geetha Palasubramaniam, Selvi Navaratnam, Parasakthi Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. |
| title | Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. |
| title_full | Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. |
| title_fullStr | Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. |
| title_full_unstemmed | Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. |
| title_short | Carbapenem-resistant Pseudomonas aeruginosa in malaysia producing IMP-7 beta-lactamase. |
| title_sort | carbapenem resistant pseudomonas aeruginosa in malaysia producing imp 7 beta lactamase |
| topic | R Medicine (General) |
| work_keys_str_mv | AT hosiaweng carbapenemresistantpseudomonasaeruginosainmalaysiaproducingimp7betalactamase AT subramaniamgeetha carbapenemresistantpseudomonasaeruginosainmalaysiaproducingimp7betalactamase AT palasubramaniamselvi carbapenemresistantpseudomonasaeruginosainmalaysiaproducingimp7betalactamase AT navaratnamparasakthi carbapenemresistantpseudomonasaeruginosainmalaysiaproducingimp7betalactamase |