Calcitriol (1,25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis
Calcitriol (1,25-dihydroxycholecalciferol) has antiproliferative and/or proapoptotic effects on many cell types and the glucocorticoid dexamethasone enhances these effects. We have shown that calcitriol modulates several key signaling proteins involved in differentiation, proliferation and apoptosis...
Main Authors: | Flynn, G., Chung, I., Yu, W.D., Romano, M., Modzelewski, R.A., Johnson, C.S., Trump, D.L. |
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Format: | Article |
Language: | English |
Published: |
2006
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Subjects: | |
Online Access: | http://eprints.um.edu.my/5070/1/Flynn-2006-Calcitriol_%281%2C25-dih.pdf |
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