Knockdown of antizyme inhibitor decreases prostate tumor growth in vivo

Knockdown of antizyme inhibitor decreases prostate tumor growth in vivo

The endogenous protein antizyme inhibitor (AZI) is a potential oncogene which promotes cell growth by both inhibiting antizyme (AZ) activity and releasing ornithine decarboxylase (ODC) from AZ-mediated degradation. High levels of ODC and polyamines are associated with numerous types of neoplastic tr...

Full description

Bibliographic Details
Main Authors:	Olsen, R.R., Chung, I., Zetter, B.R.
Format:	Article
Language:	English
Published:	2012
Subjects:	R Medicine
Online Access:	http://eprints.um.edu.my/5081/1/Olsen-2012-Knockdown_of_antizym.pdf

Similar Items

Antizyme inhibitor family: biological and translational research implications
by: Qiaohui Feng, et al.
Published: (2024-01-01)

Alpha-tomatine attenuation of in vivo growth of subcutaneous and orthotopic xenograft tumors of human prostate carcinoma Pc-3 cells is accompanied by inactivation of nuclear factor-kappa b signaling
by: Lee, S.T., et al.
Published: (2013)

A role for collagen XXIII in cancer cell adhesion, anchorage-independence and metastasis.
by: Spivey, K.A., et al.
Published: (2012)

Polyamines directly promote antizyme-mediated degradation of ornithine decarboxylase by the proteasome
by: R. Roshini Beenukumar, et al.
Published: (2015-05-01)

Role of vitamin D receptor in the antiproliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo
by: Chung, I., et al.
Published: (2009)

Rescue of paclitaxel sensitivity by repression of Prohibitin1 in drug-resistant cancer cells
by: Patel, Nish, et al.
Published: (2010)

Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol
by: Chung, I., et al.
Published: (2007)

The association of Streptococcus bovis/gallolyticus with colorectal tumors: The nature and the underlying mechanisms of its etiological role.
by: Abdulamir, A.S., et al.
Published: (2011)

Alpha-tomatine synergises with paclitaxel to enhance apoptosis of androgen-independent human prostate cancer PC-3 cells in vitro and in vivo
by: Lee, Sui-Ting, et al.
Published: (2013)

Analytical solution of reaction-diffusion equations for calcium wave propagation in a starburst amacrine cell
by: Poznanski, R.R.
Published: (2010)

Cellular inhibitory behavior underlying the formation of retinal direction selectivity in the starburst network
by: Poznanski, R.R.
Published: (2010)

Cholinergic control of growth hormone (GH) responses to GH-releasing hormone in insulin dependent diabetics: evidence for attenuated hypothalamic somatostatinergic tone and decreased GH autofeedback
by: Ismail, I.S., et al.
Published: (1993)

Synthesis and anticancer activity of novel water soluble benzimidazole carbamates
by: Cheong, Jae Eun, et al.
Published: (2018)

Urine of patients with early prostate cancer contains lower levels of light chain fragments of inter-alpha-trypsin inhibitor and saposin B but increased expression of an inter-alpha-trypsin inhibitor heavy chain 4 fragment
by: Jayapalan, J.J., et al.
Published: (2013)

The usefulness of prostate specific antigen density in prostate cancer detection: a Malaysian perspective
by: Shanggar, K., et al.
Published: (2010)

Contrast media induced transient cortical blindness
by: Balasingam, S., et al.
Published: (2016)

Epigenetic silencing of CYP24 in the tumor microenvironment
by: Johnson, C.S., et al.
Published: (2010)

In vivo encystation of Blastocystis hominis
by: Suresh, K., et al.
Published: (2009)

Report of the forth Asian Prostate Cancer (A-CaP) study meeting
by: Youl Lee, Ji, et al.
Published: (2019)

Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: Wild type and mutant (L1196M) active compounds with unique binding mode
by: Gummadi, V.R., et al.
Published: (2013)

Chitosan complexed carboxymethylated iota-carrageenan oral insulin particles: Stability, permeability and in vivo evaluation
by: Sahoo, Pratyusa, et al.
Published: (2019)

Interleukin-6 Is Required for Pancreatic Cancer Progression by Promoting MAPK Signaling Activation and Oxidative Stress Resistance
by: Zhang, Yaqing, et al.
Published: (2013)

Adult female with acute renal failure and weight loss
by: Abdul-Rahman, N.A., et al.
Published: (2016)

United in Fight against prOstate cancer (UFO) registry: first results from a large, multi-centre, prospective, longitudinal cohort study of advanced prostate cancer in Asia
by: Uemura, Hirotsugu, et al.
Published: (2020)

Thymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitro
by: Salim, L.Z.A., et al.
Published: (2014)

Successful pregnancy with epidermal growth factor receptor tyrosine kinase inhibitor treatment of metastatic lung adenocarcinoma presenting with respiratory failure
by: Lee, C.H., et al.
Published: (2011)

Role of liquid membrane phenomenon in biological actions of ACE inhibitors, captopril and lisinopril
by: Nagappa, A.N., et al.
Published: (2001)

Overactive bladder (OAB) and its association with prostatic parameters
by: Tan, W.S., et al.
Published: (2011)

Calcitriol (1,25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis
by: Flynn, G., et al.
Published: (2006)

Growth medium with low serum and transforming growth factor beta 3 promotes better chondrogenesis of bone marrow-derived stem cells in vitro and in vivo
by: Alfaqeh, Hamoud Hussein Mohammed, et al.
Published: (2011)

Identification of potential complementary serum biomarkers to differentiate prostate cancer from benign prostatic hyperplasia using gel- and lectin-based proteomics analyses
by: Jayapalan, J.J., et al.
Published: (2012)

Structural and functional divergence of the newly identified GtrIc from its Gtr family of conserved Shigella flexneri serotype-converting glucosyltransferases
by: Ramiscal, R.R., et al.
Published: (2010)

Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study
by: Adams, Charleen D., et al.
Published: (2018)

Impact of saffron as an anti-cancer and anti-tumor herb
by: Chermahini, S.H., et al.
Published: (2010)

Awareness of prostatism among male patients in Teluk Intan Hospital
by: Zainal, S.B., et al.
Published: (2005)

Heterogenous expression of ERG oncoprotein in Malaysian men with adenocarcinoma of the prostate
by: Tan, Jia Shin Jessica, et al.
Published: (2018)

Dentatin Induces Apoptosis in Prostate Cancer Cells via Bcl-2, Bcl-xL, Survivin Downregulation, Caspase-9, -3/7 Activation, and NF-κB Inhibition
by: Arbab, I.A., et al.
Published: (2012)

In Vitro and In Vivo Anti-Angiogenic Activities of Panduratin A
by: Lai, Siew Li, et al.
Published: (2012)

Doxorubicin-loaded micelles of amphiphilic diblock copolymer with pendant dendron improve antitumor efficacy: In vitro and in vivo studies
by: Voon, Siew Hui, et al.
Published: (2017)

Inhibition of microvesiculation sensitizes prostate cancer cells to chemotherapy and reduces docetaxel dose required to limit tumor growth in vivo
by: Jorfi, Samireh, et al.
Published: (2015)