Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy

Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy

Approximately one third of newly treated epilepsy patients do not respond to antiepileptic drugs (AEDs). Overexpression of P-glycoprotein (P-gp) efflux transporter has been proposed to have a critical role in causing resistance to AEDs. P-gp is a product of the ATP-binding cassette subfamily B membe...

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Bibliographic Details
Main Authors: Haerian, B.S., Lim, K.S., Mohamed, E.H.M., Tan, H.J., Tan, C.T., Raymond, A.A., Wong, C.P., Wong, S.W., Mohamed, Z.
Format: Article
Language:English
Published: 2011
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/5088/1/Haerian-2011-Lack_of_association.pdf

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