Acute toxicity and gastroprotective effect of the Schiff base ligand ¹H-indole-3-ethylene-5-nitrosalicylaldimine and its nickel (II) complex on ethanol induced gastric lesions in rats

Acute toxicity and gastroprotective effect of the Schiff base ligand ¹H-indole-3-ethylene-5-nitrosalicylaldimine and its nickel (II) complex on ethanol induced gastric lesions in rats

Show other versions (1)

The present study was performed to evaluate the gastroprotective activity of Schiff base ligand derived from the condensation reaction of tryptamine (an indole derivative) and 5-nitrosalicylaldehyde (TNS) and its nickel (II) complex against ethanol-induced gastric ulcer in rats. The compounds were o...

Full description

Bibliographic Details
Main Authors:	Ibrahim, M.M., Ali, Hapipah Mohd, Abdullah, M.A., Hassandarvish, P.
Format:	Article
Language:	English
Published:	MDPI 2012
Subjects:	QD Chemistry
Online Access:	http://eprints.um.edu.my/5140/1/Ibrahim-2012-Acute_toxicity_and_g.pdf

Similar Items

Acute toxicity and gastroprotective effect of the schiff base ligand 1H-indole-3-ethylene-5-nitrosalicylaldimine and its nickel (II) complex on ethanol induced gastric lesions in rats
by: Abdullah, M.A., et al.
Published: (2012)

Acute Toxicity and Gastroprotective Effect of the Schiff Base Ligand 1H-Indole-3-ethylene-5-nitrosalicylaldimine and Its Nickel (II) Complex on Ethanol Induced Gastric Lesions in Rats
by: Pouya Hassandarvish, et al.
Published: (2012-10-01)

Gastroprotection studies of Schiff Base Zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats
by: Golbabapour, S., et al.
Published: (2013)

Gastroprotective effects of melastoma malabathricum aqueous leaf extract against ethanol-induced gastric ulcer in rats
by: Hussain, F., et al.
Published: (2008)

Coordination behavior of three geometric isomers of indole-based s-benzyldithiocarbazone ligands towards nickel, zinc and cadmium divalent ions
by: Khaledi, H., et al.
Published: (2011)

Synthesis of 2 '-(5-Chloro-2-Hydroxybenzylidene) benzenesulfanohydrazide schiff base and its anti-ulcer activity in ethanol-induced gastric mucosal lesions in rats
by: Gwaram, N.S., et al.
Published: (2012)

Acute toxicity and gastroprotection studies of a new schiff base derived copper (II) complex against ethanol-induced acute gastric lesions in rats.
by: Maryam Hajrezaie, et al.
Published: (2012-01-01)

Acute toxicity and gastroprotection studies of a newSchiff base derived copper (II) complex against ethanol-induced acute gastric lesions in rats
by: Abdulla, M.A., et al.
Published: (2012)

Cytoprotective effect of benzyl n'-(5-chloro-indol-3-ylmethylidene)- hydrazinecarbodithioate against ethanol-induced gastric mucosal injury in rats
by: Hashim, H., et al.
Published: (2012)

Gastroprotective Effect of Ethanolic Extract of Curcuma xanthorrhiza Leaf against Ethanol-Induced Gastric Mucosal Lesions in Sprague-Dawley Rats
by: Rahim, N.A., et al.
Published: (2014)

Benzyl N '-(1H-indol-2-ylmethylene)hydrazinecarbodithioate ethanol hemisolvate
by: Khaledi, H., et al.
Published: (2008)

Gastroprotective activity and mechanism of novel dichlorido-zinc(II)-4-(2-(5-methoxybenzylideneamino)ethyl)piperazin-1-iumphenolate complex on ethanol-induced gastric ulceration
by: Salga, Muhammad Saleh, et al.
Published: (2012)

Antioxidant, cytotoxic activities, and structure-activity relationship of gallic acid-based indole derivatives
by: Khaledi, H., et al.
Published: (2011)

Synthesis, structural characterization and in vitro cytotoxicity of diorganotin complexes with schiff base ligands derived from3-hydroxy-2-naphthoylhydrazide
by: Mun, L.S., et al.
Published: (2012)

trans-Bis(1H-indole-3-carbaldehyde thiosemicarbazonato-κ2 N 1,S)nickel(II)
by: Rizal, Mohd Razali, et al.
Published: (2008)

Gastroprotection studies of Schiff base zinc (II) derivative complex against acute superficial hemorrhagic mucosal lesions in rats.
by: Shahram Golbabapour, et al.
Published: (2013-01-01)

Schiff base metal derivatives enhance the expression of HSP70 and suppress BAX proteins in prevention of acute gastric lesion
by: Golbabapour, S., et al.
Published: (2013)

Indole-7-carbaldehyde thiosemicarbazone as a flexidentate ligand toward ZnII, CdII, PdII and PtII ions: cytotoxic and apoptosis-inducing properties of the PtII complex
by: Ibrahim, A.A., et al.
Published: (2014)

Indole-7-carbaldehyde thiosemicarbazone as a flexidentate ligand toward ZnII, CdII, PdII and PtII ions: cytotoxic and apoptosis-inducing properties of the PtII complex
by: Ibrahim, A.A., et al.
Published: (2013)

Gastroprotective activity of a novel Schiff base derived dibromo substituted compound against ethanol-induced acute gastric lesions in rats
by: Saremi, Kamelia, et al.
Published: (2019)

Gastroprotective activity of a novel Schiff base derived dibromo substituted compound against ethanol-induced acute gastric lesions in rats
by: Kamelia Saremi, et al.
Published: (2019-02-01)

Bis benzyl N '-(1H-indol-3-ylmethylene)hydrazinecarbodithioato-kappa(2)N ',S nickel(II) N,N-dimethylformamide disolvate
by: Khaledi, H., et al.
Published: (2008)

Synthesis and gastroprotective activities of some zinc (II) complexes derived from (E)-2-(1-(2-(piperazin-1-yl)ethylimino)ethyl)phenol and (E)-4-(1-(2-(piperazin-1-yl)ethylimino)ethyl)benzene-1,3-diol Schiff bases against aspirin induced ulceration
by: Salga, M.S., et al.
Published: (2017)

1H-Indole-3-carbaldehyde thiosemicarbazone
by: Rizal, R.M., et al.
Published: (2008)

Bis(2-methyl-1H-indole-3-carbaldehyde 4-hydroxy-benzoylhydrazonato-kappa N-2,O)nickel(II) N,N-dimethylformamide disolvate dihydrate
by: Ali, Hapipah Mohd, et al.
Published: (2006)

Bis[1,5-bis(1H-indol-3-ylmethylene)thiocarbazonato-κ2 N,S]nickel(II) dimethyl sulfoxide disolvate
by: Rizal, Mohd Razali, et al.
Published: (2008)

2-(1H-indol-3-yl)-2 '-(1H-indol-3-yl-methylene)acetohydrazide
by: Ali, Hapipah Mohd, et al.
Published: (2007)

Anti-ulcerogenic activity of aqueous extract of ficus deltoidea against ethanol-induced gastric mucosal injury in rats
by: Zahra, M.A.S.F., et al.
Published: (2009)

5-Methyl-1H-indole-3-carbaldehyde
by: Ismail, S.S., et al.
Published: (2012)

5-chloro-1H-indole-3-carbaldehyde benzoylhydrazone
by: Ali, Hapipah Mohd, et al.
Published: (2006)

Bis[5-bromo-1 H-indole-3-carbaldehyde (2-nitro-benzoyl)hydrazonato- κ2N,O]bis(pyridine-κ:N)-nickel(II) pyridine disolvate
by: Ali, Hapipah Mohd, et al.
Published: (2005)

2-methyl-1H-indole-3-carbaldehyde 4-hydroxybenzoylhydrazone
by: Ali, Hapipah Mohd, et al.
Published: (2006)

2-methyl-1H-indole-3-carbaldehyde 2-thienoylhydrazone
by: Ali, Hapipah Mohd, et al.
Published: (2006)

5-chloro-1H-indole-3-carbaldehyde 4-chlorobenzoylhydrazone
by: Ali, Hapipah Mohd, et al.
Published: (2006)

Gastroprotective property of Pseudocydonia sinensis fruit jelly on the ethanol-induced gastric lesions in rats
by: Yasunori Hamauzu, et al.
Published: (2018-09-01)

Benzyl N '-(1H-indol-3-ylmethylidene)-hydrazinecarbodithioate
by: Khaledi, H., et al.
Published: (2008)

2 '- (5-chloro-1H-indol-3-yl)methylene 2-(1H-indol-3-yl)acetohydrazide
by: Ali, Hapipah Mohd, et al.
Published: (2007)

2'- (5-bromo-1H-indol-3-yl)methylene -2-(1H-indol-3-yl)acetohydrazide ethyl acetate solvate
by: Ali, Hapipah Mohd, et al.
Published: (2007)

Synthesis, structural characterization, and anti-ulcerogenic activity of schiff base ligands derived from tryptamine and 5-chloro, 5-nitro, 3,5-ditertiarybutyl salicylaldehyde and their nickel(II), copper(II), and Zinc(II) complexes
by: Mustafa, Iman Mohamed, et al.
Published: (2009)

Biochanin a gastroprotective effects in ethanol-induced gastric mucosal ulceration in rats.
by: Maryam Hajrezaie, et al.
Published: (2015-01-01)