Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
2012
|
Subjects: | |
Online Access: | http://eprints.um.edu.my/5429/1/Antibacterial_Evaluation_of_Some_Schiff_Bases_Derived_from_2-Acetylpyridine_and_Their_Metal_Complexes.pdf |
_version_ | 1825719094040592384 |
---|---|
author | Gwaram, N.S. Ali, H.M. Khaledi, H. Abdulla, M.A. Hadi, A.H.A. Thong, Kwai Lin Ching, C.L. Ooi, C.L. |
author_facet | Gwaram, N.S. Ali, H.M. Khaledi, H. Abdulla, M.A. Hadi, A.H.A. Thong, Kwai Lin Ching, C.L. Ooi, C.L. |
author_sort | Gwaram, N.S. |
collection | UM |
description | A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa. |
first_indexed | 2024-03-06T05:14:24Z |
format | Article |
id | um.eprints-5429 |
institution | Universiti Malaya |
language | English |
last_indexed | 2024-03-06T05:14:24Z |
publishDate | 2012 |
record_format | dspace |
spelling | um.eprints-54292019-01-30T01:27:41Z http://eprints.um.edu.my/5429/ Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes Gwaram, N.S. Ali, H.M. Khaledi, H. Abdulla, M.A. Hadi, A.H.A. Thong, Kwai Lin Ching, C.L. Ooi, C.L. Q Science (General) QR Microbiology A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa. 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/5429/1/Antibacterial_Evaluation_of_Some_Schiff_Bases_Derived_from_2-Acetylpyridine_and_Their_Metal_Complexes.pdf Gwaram, N.S. and Ali, H.M. and Khaledi, H. and Abdulla, M.A. and Hadi, A.H.A. and Thong, Kwai Lin and Ching, C.L. and Ooi, C.L. (2012) Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes. Molecules, 17 (5). pp. 5952-5971. ISSN 1420-3049, DOI https://doi.org/10.3390/molecules17055952 <https://doi.org/10.3390/molecules17055952>. 10.3390/molecules17055952 |
spellingShingle | Q Science (General) QR Microbiology Gwaram, N.S. Ali, H.M. Khaledi, H. Abdulla, M.A. Hadi, A.H.A. Thong, Kwai Lin Ching, C.L. Ooi, C.L. Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
title | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
title_full | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
title_fullStr | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
title_full_unstemmed | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
title_short | Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes |
title_sort | antibacterial evaluation of some schiff bases derived from 2 acetylpyridine and their metal complexes |
topic | Q Science (General) QR Microbiology |
url | http://eprints.um.edu.my/5429/1/Antibacterial_Evaluation_of_Some_Schiff_Bases_Derived_from_2-Acetylpyridine_and_Their_Metal_Complexes.pdf |
work_keys_str_mv | AT gwaramns antibacterialevaluationofsomeschiffbasesderivedfrom2acetylpyridineandtheirmetalcomplexes AT alihm antibacterialevaluationofsomeschiffbasesderivedfrom2acetylpyridineandtheirmetalcomplexes AT khaledih antibacterialevaluationofsomeschiffbasesderivedfrom2acetylpyridineandtheirmetalcomplexes AT abdullama antibacterialevaluationofsomeschiffbasesderivedfrom2acetylpyridineandtheirmetalcomplexes AT hadiaha antibacterialevaluationofsomeschiffbasesderivedfrom2acetylpyridineandtheirmetalcomplexes AT thongkwailin antibacterialevaluationofsomeschiffbasesderivedfrom2acetylpyridineandtheirmetalcomplexes AT chingcl antibacterialevaluationofsomeschiffbasesderivedfrom2acetylpyridineandtheirmetalcomplexes AT ooicl antibacterialevaluationofsomeschiffbasesderivedfrom2acetylpyridineandtheirmetalcomplexes |