Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes

A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni...

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Main Authors: Gwaram, N.S., Ali, H.M., Khaledi, H., Abdulla, M.A., Hadi, A.H.A., Thong, Kwai Lin, Ching, C.L., Ooi, C.L.
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:http://eprints.um.edu.my/5429/1/Antibacterial_Evaluation_of_Some_Schiff_Bases_Derived_from_2-Acetylpyridine_and_Their_Metal_Complexes.pdf
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author Gwaram, N.S.
Ali, H.M.
Khaledi, H.
Abdulla, M.A.
Hadi, A.H.A.
Thong, Kwai Lin
Ching, C.L.
Ooi, C.L.
author_facet Gwaram, N.S.
Ali, H.M.
Khaledi, H.
Abdulla, M.A.
Hadi, A.H.A.
Thong, Kwai Lin
Ching, C.L.
Ooi, C.L.
author_sort Gwaram, N.S.
collection UM
description A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa.
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spelling um.eprints-54292019-01-30T01:27:41Z http://eprints.um.edu.my/5429/ Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes Gwaram, N.S. Ali, H.M. Khaledi, H. Abdulla, M.A. Hadi, A.H.A. Thong, Kwai Lin Ching, C.L. Ooi, C.L. Q Science (General) QR Microbiology A series of Schiff bases derived from 2-acetylpyridne and their metal complexes were characterized by elemental analysis, NMR, FT-IR and UV-Vis spectral studies. The complexes were screened for anti-bacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumanni (AC), Klebsiella pneumonie (KB) and Pseudomonas aeruginosa (PA) using the disc diffusion and micro broth dilution assays. Based on the overall results, the complexes showed the highest activities against MRSA while a weak antibacterial activity was observed against A. baumanii and P. aeruginosa. 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/5429/1/Antibacterial_Evaluation_of_Some_Schiff_Bases_Derived_from_2-Acetylpyridine_and_Their_Metal_Complexes.pdf Gwaram, N.S. and Ali, H.M. and Khaledi, H. and Abdulla, M.A. and Hadi, A.H.A. and Thong, Kwai Lin and Ching, C.L. and Ooi, C.L. (2012) Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes. Molecules, 17 (5). pp. 5952-5971. ISSN 1420-3049, DOI https://doi.org/10.3390/molecules17055952 <https://doi.org/10.3390/molecules17055952>. 10.3390/molecules17055952
spellingShingle Q Science (General)
QR Microbiology
Gwaram, N.S.
Ali, H.M.
Khaledi, H.
Abdulla, M.A.
Hadi, A.H.A.
Thong, Kwai Lin
Ching, C.L.
Ooi, C.L.
Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_full Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_fullStr Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_full_unstemmed Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_short Antibacterial Evaluation of Some Schiff Bases Derived from 2-Acetylpyridine and Their Metal Complexes
title_sort antibacterial evaluation of some schiff bases derived from 2 acetylpyridine and their metal complexes
topic Q Science (General)
QR Microbiology
url http://eprints.um.edu.my/5429/1/Antibacterial_Evaluation_of_Some_Schiff_Bases_Derived_from_2-Acetylpyridine_and_Their_Metal_Complexes.pdf
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