Boesenbergia rotunda: From Ethnomedicine to Drug Discovery

Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly used as a food ingredient and in ethnomedicinal preparations. The popularity of its ethnomedicinal usage has drawn the attention of scientist...

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Main Authors: Eng-Chong, T., Yean-Kee, L., Chin-Fei, C., Choon-Han, H., Sher-Ming, W., Li-Ping, C.T., Gen-Teck, F., Khalid, Norzulaani, Abd Rahman, N., Karsani, S.A., Othman, S., Othman, R., Yusof, R.
Format: Article
Language:English
Published: Hindawi 2012
Subjects:
Online Access:http://eprints.um.edu.my/5891/1/Boesenbergia_rotunda_From_Ethnomedicine_to_Drug_Discovery.pdf
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author Eng-Chong, T.
Yean-Kee, L.
Chin-Fei, C.
Choon-Han, H.
Sher-Ming, W.
Li-Ping, C.T.
Gen-Teck, F.
Khalid, Norzulaani
Abd Rahman, N.
Karsani, S.A.
Othman, S.
Othman, R.
Yusof, R.
author_facet Eng-Chong, T.
Yean-Kee, L.
Chin-Fei, C.
Choon-Han, H.
Sher-Ming, W.
Li-Ping, C.T.
Gen-Teck, F.
Khalid, Norzulaani
Abd Rahman, N.
Karsani, S.A.
Othman, S.
Othman, R.
Yusof, R.
author_sort Eng-Chong, T.
collection UM
description Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly used as a food ingredient and in ethnomedicinal preparations. The popularity of its ethnomedicinal usage has drawn the attention of scientists worldwide to further investigate its medicinal properties. Advancement in drug design and discovery research has led to the development of synthetic drugs from B. rotunda metabolites via bioinformatics and medicinal chemistry studies. Furthermore, with the advent of genomics, transcriptomics, proteomics, and metabolomics, new insights on the biosynthetic pathways of B. rotunda metabolites can be elucidated, enabling researchers to predict the potential bioactive compounds responsible for the medicinal properties of the plant. The vast biological activities exhibited by the compounds obtained from B. rotunda warrant further investigation through studies such as drug discovery, polypharmacology, and drug delivery using nanotechnology.
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spelling um.eprints-58912020-01-29T06:30:36Z http://eprints.um.edu.my/5891/ Boesenbergia rotunda: From Ethnomedicine to Drug Discovery Eng-Chong, T. Yean-Kee, L. Chin-Fei, C. Choon-Han, H. Sher-Ming, W. Li-Ping, C.T. Gen-Teck, F. Khalid, Norzulaani Abd Rahman, N. Karsani, S.A. Othman, S. Othman, R. Yusof, R. QH301 Biology Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly used as a food ingredient and in ethnomedicinal preparations. The popularity of its ethnomedicinal usage has drawn the attention of scientists worldwide to further investigate its medicinal properties. Advancement in drug design and discovery research has led to the development of synthetic drugs from B. rotunda metabolites via bioinformatics and medicinal chemistry studies. Furthermore, with the advent of genomics, transcriptomics, proteomics, and metabolomics, new insights on the biosynthetic pathways of B. rotunda metabolites can be elucidated, enabling researchers to predict the potential bioactive compounds responsible for the medicinal properties of the plant. The vast biological activities exhibited by the compounds obtained from B. rotunda warrant further investigation through studies such as drug discovery, polypharmacology, and drug delivery using nanotechnology. Hindawi 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/5891/1/Boesenbergia_rotunda_From_Ethnomedicine_to_Drug_Discovery.pdf Eng-Chong, T. and Yean-Kee, L. and Chin-Fei, C. and Choon-Han, H. and Sher-Ming, W. and Li-Ping, C.T. and Gen-Teck, F. and Khalid, Norzulaani and Abd Rahman, N. and Karsani, S.A. and Othman, S. and Othman, R. and Yusof, R. (2012) Boesenbergia rotunda: From Ethnomedicine to Drug Discovery. Evidence-Based Complementary and Alternative Medicine, 2012. p. 473637. ISSN 1741-427X, DOI https://doi.org/10.1155/2012/473637 <https://doi.org/10.1155/2012/473637>. 10.1155/2012/473637
spellingShingle QH301 Biology
Eng-Chong, T.
Yean-Kee, L.
Chin-Fei, C.
Choon-Han, H.
Sher-Ming, W.
Li-Ping, C.T.
Gen-Teck, F.
Khalid, Norzulaani
Abd Rahman, N.
Karsani, S.A.
Othman, S.
Othman, R.
Yusof, R.
Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
title Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
title_full Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
title_fullStr Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
title_full_unstemmed Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
title_short Boesenbergia rotunda: From Ethnomedicine to Drug Discovery
title_sort boesenbergia rotunda from ethnomedicine to drug discovery
topic QH301 Biology
url http://eprints.um.edu.my/5891/1/Boesenbergia_rotunda_From_Ethnomedicine_to_Drug_Discovery.pdf
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