Transforming growth factor-beta enhances invasion and metastasis in Ras-transfected human malignant epidermal keratinocytes

Transforming growth factor-beta enhances invasion and metastasis in Ras-transfected human malignant epidermal keratinocytes

Transforming growth factor- beta(TGF-beta) is known to act as a tumour suppressor early in carcinogenesis, but then switches to a pro-metastatic factor in some late stage cancers. However, the actions of TGF-beta are context dependent, and it is currently unclear how TGF-beta influences the progress...

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Bibliographic Details
Main Authors: Davies, M., Prime, S.S., Eveson, J.W., Price, N., Ganapathy, A., D'Mello, A., Paterson, I.C.
Format: Article
Language:English
Published: Blackwell Publishing 2012
Subjects:
RK Dentistry
Online Access:http://eprints.um.edu.my/6035/1/Transforming_growth_factor-beta_enhances_invasion_and_metastasis_in_Ras-transfected_human_malignant_epidermal_keratinocytes.pdf

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