Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation
A top down approach based on emulsification-evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storag...
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| Format: | Article |
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2008
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| author | Cheong, J.N. Tan, C.P. Man, Y.B.C. Misran, M. |
| author_facet | Cheong, J.N. Tan, C.P. Man, Y.B.C. Misran, M. |
| author_sort | Cheong, J.N. |
| collection | UM |
| description | A top down approach based on emulsification-evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storage study was performed for 3 months to evaluate the stability of all the prepared nanodispersions. The results showed that homogenization pressure have significant (P < 0.05) influence on the droplet diameter and size distribution. On the contrary, the processing cycle had not significant (P > 0.05) effect on the droplet diameter and size distribution of the prepared nanodispersion. Droplet diameters in the range of 90-120 nm were obtained for the prepared α-tocopherol nanodispersions. During storage duration, there were no significant (P > 0.05) changes in mean diameters while the concentrations of α-tocopherol were significantly (P < 0.05) reduced for all prepared nanodispersions. In general, it is shown that emulsification-evaporation technique can be used as a suitable technique for the production of α-tocopherol nanodispersions with narrow size distribution. |
| first_indexed | 2024-03-06T05:17:23Z |
| format | Article |
| id | um.eprints-6878 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:17:23Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | um.eprints-68782013-07-09T01:21:09Z http://eprints.um.edu.my/6878/ Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation Cheong, J.N. Tan, C.P. Man, Y.B.C. Misran, M. QD Chemistry A top down approach based on emulsification-evaporation technique was used to prepare nanodispersion of α-tocopherol. Physicochemical properties of the prepared nanodispersions were investigated under combination of the processing parameters (pressure and cycle) and ratio of aqueous:organic. Storage study was performed for 3 months to evaluate the stability of all the prepared nanodispersions. The results showed that homogenization pressure have significant (P < 0.05) influence on the droplet diameter and size distribution. On the contrary, the processing cycle had not significant (P > 0.05) effect on the droplet diameter and size distribution of the prepared nanodispersion. Droplet diameters in the range of 90-120 nm were obtained for the prepared α-tocopherol nanodispersions. During storage duration, there were no significant (P > 0.05) changes in mean diameters while the concentrations of α-tocopherol were significantly (P < 0.05) reduced for all prepared nanodispersions. In general, it is shown that emulsification-evaporation technique can be used as a suitable technique for the production of α-tocopherol nanodispersions with narrow size distribution. 2008 Article PeerReviewed Cheong, J.N. and Tan, C.P. and Man, Y.B.C. and Misran, M. (2008) Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation. Journal of Food Engineering, 89 (2). pp. 204-209. ISSN 02608774 , DOI https://doi.org/10.1016/j.jfoodeng.2008.04.018 <https://doi.org/10.1016/j.jfoodeng.2008.04.018>. 10.1016/j.jfoodeng.2008.04.018 |
| spellingShingle | QD Chemistry Cheong, J.N. Tan, C.P. Man, Y.B.C. Misran, M. Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
| title | Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
| title_full | Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
| title_fullStr | Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
| title_full_unstemmed | Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
| title_short | Alpha-tocopherol nanodispersions: preparation, characterization and stability evaluation |
| title_sort | alpha tocopherol nanodispersions preparation characterization and stability evaluation |
| topic | QD Chemistry |
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