Factors affecting nucleolytic efficiency of some ternary metal complexes with DNA binding and recognition domains. Crystal and molecular structure of Zn(phen)(edda)

Factors affecting nucleolytic efficiency of some ternary metal complexes with DNA binding and recognition domains. Crystal and molecular structure of Zn(phen)(edda)

The binding selectivity of the M(phen)(edda) (M = Cu, Co, Ni, Zn; phen = 1,10-phenanthroline, edda = ethylenediaminediacetic acid) complexes towards ds(CG)(6), ds(AT)(6) and ds(CGCGAATTCGCG) B-form oligonucleotide duplexes were studied by CD spectroscopy and molecular modeling. The binding mode is i...

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Bibliographic Details
Main Authors:	Seng, H.L., Ng, C.H., Caracelli, I., Maah, M.J., Tan, K.W., Tiekink, E.R.T., Yamin, B.M., Rahman, R.N., Ong, H.K.A.
Format:	Article
Published:	2008
Subjects:	QD Chemistry

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