Pharmacophore based synthesis of 3-chloroquinoxaline-2-carboxamides as serotonin(3) (5-HT3) receptor antagonist

A series of 3-chloroquinoxaline-2-carboxamides were designed and prepared by the condensation of 3-chloro-2-quinoxaloylchloride with appropriate Mannich bases of the p-aminophenol in the microwave environment. The synthesized compounds were evaluated for serotonin(3) (5-HT3) receptor antagonistic ac...

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Main Authors: Mahesh, R., Perumal, R.V., Pandi, P.V.
格式: 文件
语言:English
出版: 2004
主题:
在线阅读:http://eprints.um.edu.my/8137/1/Mahesh-2004-Pharmacophore_Based.pdf