Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity
epato-toxicity is a common toxicity happening during the treatment of chronic diseases like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region used as laxative, sedative, anti-cancer and also consist of glycosides, flavonoids, anthocyanins, vitamins. I...
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author | Manokaran, S. Saravanan, V.S. Bhargavi, Y. Pandi, P.V. |
author_facet | Manokaran, S. Saravanan, V.S. Bhargavi, Y. Pandi, P.V. |
author_sort | Manokaran, S. |
collection | UM |
description | epato-toxicity is a common toxicity happening during the treatment of chronic diseases like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region used as laxative, sedative, anti-cancer and also consist of glycosides, flavonoids, anthocyanins, vitamins. It also possess hepato-protactent property. To prove the activity scientifically the ethanolic extract of Prunus persica was studied against Paracetamol induced Hepatotoxicity in albino rats. The extract when evaluated at the dose of 100mg / kg was found to significantly reduce the elevated levels of serum Lysosomal enzyme SGPT, SGOT, ALP and Bilirubin when compared with standard Silymarin. |
first_indexed | 2024-03-06T05:20:35Z |
format | Article |
id | um.eprints-8145 |
institution | Universiti Malaya |
last_indexed | 2024-03-06T05:20:35Z |
publishDate | 2011 |
record_format | dspace |
spelling | um.eprints-81452013-07-22T01:44:01Z http://eprints.um.edu.my/8145/ Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity Manokaran, S. Saravanan, V.S. Bhargavi, Y. Pandi, P.V. R Medicine epato-toxicity is a common toxicity happening during the treatment of chronic diseases like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region used as laxative, sedative, anti-cancer and also consist of glycosides, flavonoids, anthocyanins, vitamins. It also possess hepato-protactent property. To prove the activity scientifically the ethanolic extract of Prunus persica was studied against Paracetamol induced Hepatotoxicity in albino rats. The extract when evaluated at the dose of 100mg / kg was found to significantly reduce the elevated levels of serum Lysosomal enzyme SGPT, SGOT, ALP and Bilirubin when compared with standard Silymarin. 2011 Article PeerReviewed Manokaran, S. and Saravanan, V.S. and Bhargavi, Y. and Pandi, P.V. (2011) Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity. Research Journal of Pharmacognosy and Phytochemistry, 3 (2). pp. 75-76. ISSN 0975-4385, |
spellingShingle | R Medicine Manokaran, S. Saravanan, V.S. Bhargavi, Y. Pandi, P.V. Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity |
title | Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity |
title_full | Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity |
title_fullStr | Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity |
title_full_unstemmed | Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity |
title_short | Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity |
title_sort | hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity |
topic | R Medicine |
work_keys_str_mv | AT manokarans hepatoprotectiveactivityofprunuspersicapeachesagainstparacetamolinducedhepatotoxicity AT saravananvs hepatoprotectiveactivityofprunuspersicapeachesagainstparacetamolinducedhepatotoxicity AT bhargaviy hepatoprotectiveactivityofprunuspersicapeachesagainstparacetamolinducedhepatotoxicity AT pandipv hepatoprotectiveactivityofprunuspersicapeachesagainstparacetamolinducedhepatotoxicity |