Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity

epato-toxicity is a common toxicity happening during the treatment of chronic diseases like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region used as laxative, sedative, anti-cancer and also consist of glycosides, flavonoids, anthocyanins, vitamins. I...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Manokaran, S., Saravanan, V.S., Bhargavi, Y., Pandi, P.V.
Fformat: Erthygl
Cyhoeddwyd: 2011
Pynciau:
_version_ 1825719492603281408
author Manokaran, S.
Saravanan, V.S.
Bhargavi, Y.
Pandi, P.V.
author_facet Manokaran, S.
Saravanan, V.S.
Bhargavi, Y.
Pandi, P.V.
author_sort Manokaran, S.
collection UM
description epato-toxicity is a common toxicity happening during the treatment of chronic diseases like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region used as laxative, sedative, anti-cancer and also consist of glycosides, flavonoids, anthocyanins, vitamins. It also possess hepato-protactent property. To prove the activity scientifically the ethanolic extract of Prunus persica was studied against Paracetamol induced Hepatotoxicity in albino rats. The extract when evaluated at the dose of 100mg / kg was found to significantly reduce the elevated levels of serum Lysosomal enzyme SGPT, SGOT, ALP and Bilirubin when compared with standard Silymarin.
first_indexed 2024-03-06T05:20:35Z
format Article
id um.eprints-8145
institution Universiti Malaya
last_indexed 2024-03-06T05:20:35Z
publishDate 2011
record_format dspace
spelling um.eprints-81452013-07-22T01:44:01Z http://eprints.um.edu.my/8145/ Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity Manokaran, S. Saravanan, V.S. Bhargavi, Y. Pandi, P.V. R Medicine epato-toxicity is a common toxicity happening during the treatment of chronic diseases like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region used as laxative, sedative, anti-cancer and also consist of glycosides, flavonoids, anthocyanins, vitamins. It also possess hepato-protactent property. To prove the activity scientifically the ethanolic extract of Prunus persica was studied against Paracetamol induced Hepatotoxicity in albino rats. The extract when evaluated at the dose of 100mg / kg was found to significantly reduce the elevated levels of serum Lysosomal enzyme SGPT, SGOT, ALP and Bilirubin when compared with standard Silymarin. 2011 Article PeerReviewed Manokaran, S. and Saravanan, V.S. and Bhargavi, Y. and Pandi, P.V. (2011) Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity. Research Journal of Pharmacognosy and Phytochemistry, 3 (2). pp. 75-76. ISSN 0975-4385,
spellingShingle R Medicine
Manokaran, S.
Saravanan, V.S.
Bhargavi, Y.
Pandi, P.V.
Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity
title Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity
title_full Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity
title_fullStr Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity
title_full_unstemmed Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity
title_short Hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity
title_sort hepatoprotective activity of prunus persica peaches against paracetamol induced hepatotoxicity
topic R Medicine
work_keys_str_mv AT manokarans hepatoprotectiveactivityofprunuspersicapeachesagainstparacetamolinducedhepatotoxicity
AT saravananvs hepatoprotectiveactivityofprunuspersicapeachesagainstparacetamolinducedhepatotoxicity
AT bhargaviy hepatoprotectiveactivityofprunuspersicapeachesagainstparacetamolinducedhepatotoxicity
AT pandipv hepatoprotectiveactivityofprunuspersicapeachesagainstparacetamolinducedhepatotoxicity