Design and synthesis of novel quinazolinone derivatives as broad spectrum anticonvulsants
The present work was carried out to synthesize a series of substituted quinazolinone semicarbazones at third position of the quinazoline nucleus and chemically modifying second position of quinazolinone to get the compounds with lesser side effects and more potent anticonvulsive agents. Although sev...
Main Authors: | Ilangovan, P., Ganguly, S., Pandi, P.V., Stables, J.P. |
---|---|
Format: | Article |
Published: |
2010
|
Subjects: |
Similar Items
-
Pharmacophore based synthesis of 3-chloroquinoxaline-2-carboxamides as serotonin(3) (5-HT3) receptor antagonist
by: Mahesh, R., et al.
Published: (2004) -
Synthesis, characterization and apoptotic activity of quinazolinone Schiff base derivatives toward MCF-7 cells via intrinsic and extrinsic apoptosis pathways
by: Zahedifard, M., et al.
Published: (2015) -
Microwave-assisted solvent-free synthesis of 3- (4-substituted piperazin-1-yl)alkyl imidazo 2,1-b 1,3 benzothiazol-2(3H)-ones as serotonin(3) (5-HT3) receptor antagonists
by: Mahesh, R., et al.
Published: (2005) -
Synthesis of Apoptotic New Quinazolinone-Based Compound and Identification of its Underlying Mitochondrial Signalling Pathway in Breast Cancer Cells
by: Zahedifard, M., et al.
Published: (2015) -
Microwave assisted synthesis of 2-(4-substituted piperazin-1-yl)-1, 8-naphthyridine-3-carbonitrile as a new class of serotonin 5-HT< sub> 3</sub> receptor antagonists
by: Mahesh, R., et al.
Published: (2004)