Toxoplasmosis in HIV/AIDS patients in Malaysia
Three hundred and one sera of HIV/AIDS patients were tested for anti-Toxoplasma IgG antibody by ELISA technique. The seroprevalence of toxoplasmosis was 41.2 (95CI: 35.5-46.9) in HIV/AIDS patients. The seroprevalence was significantly higher in the Malay (57.9) than the Chinese (38.7), followed by t...
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| Format: | Article |
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2003
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| author | Nissapatorn, V. Lee, C.K.C. Cho, S.M. Rohela, M. Anuar, A.K. Quek, K.F. Latt, H.M. |
| author_facet | Nissapatorn, V. Lee, C.K.C. Cho, S.M. Rohela, M. Anuar, A.K. Quek, K.F. Latt, H.M. |
| author_sort | Nissapatorn, V. |
| collection | UM |
| description | Three hundred and one sera of HIV/AIDS patients were tested for anti-Toxoplasma IgG antibody by ELISA technique. The seroprevalence of toxoplasmosis was 41.2 (95CI: 35.5-46.9) in HIV/AIDS patients. The seroprevalence was significantly higher in the Malay (57.9) than the Chinese (38.7), followed by the Indian patients (29.6) (p<0.05). No possible risk factor, such as contact with cats, consumption of uncooked meat, and history of blood transfusions was found to have any significant association with the presence of anti-Toxoplasma antibody in the study sample (p > 0.05). Multivariate analysis was employed to find any association between Toxoplasma seroprevalence and a single subject having single or multiple risk factors. It was found that the association was not statistically significant (p>0.05). Among the HIV/AIDS study samples, 124 (41.2) samples were found to have positive anti-Toxoplasma antibody, the association between the presence of anti-Toxoplasma antibody and CD4 cell count was determined but no statistically significant association was found (p>0.05). During the study period, only one case of active CNS toxoplasmosis was registered and the diagnostic criteria included: clinical presentations, CT scan finding, serological evidence of anti-Toxoplasma IgG antibody, and respose to anti-Toxoplasma therapy. |
| first_indexed | 2024-03-06T05:21:18Z |
| format | Article |
| id | um.eprints-8450 |
| institution | Universiti Malaya |
| last_indexed | 2024-03-06T05:21:18Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | um.eprints-84502013-10-09T08:39:05Z http://eprints.um.edu.my/8450/ Toxoplasmosis in HIV/AIDS patients in Malaysia Nissapatorn, V. Lee, C.K.C. Cho, S.M. Rohela, M. Anuar, A.K. Quek, K.F. Latt, H.M. R Medicine Three hundred and one sera of HIV/AIDS patients were tested for anti-Toxoplasma IgG antibody by ELISA technique. The seroprevalence of toxoplasmosis was 41.2 (95CI: 35.5-46.9) in HIV/AIDS patients. The seroprevalence was significantly higher in the Malay (57.9) than the Chinese (38.7), followed by the Indian patients (29.6) (p<0.05). No possible risk factor, such as contact with cats, consumption of uncooked meat, and history of blood transfusions was found to have any significant association with the presence of anti-Toxoplasma antibody in the study sample (p > 0.05). Multivariate analysis was employed to find any association between Toxoplasma seroprevalence and a single subject having single or multiple risk factors. It was found that the association was not statistically significant (p>0.05). Among the HIV/AIDS study samples, 124 (41.2) samples were found to have positive anti-Toxoplasma antibody, the association between the presence of anti-Toxoplasma antibody and CD4 cell count was determined but no statistically significant association was found (p>0.05). During the study period, only one case of active CNS toxoplasmosis was registered and the diagnostic criteria included: clinical presentations, CT scan finding, serological evidence of anti-Toxoplasma IgG antibody, and respose to anti-Toxoplasma therapy. 2003 Article PeerReviewed Nissapatorn, V. and Lee, C.K.C. and Cho, S.M. and Rohela, M. and Anuar, A.K. and Quek, K.F. and Latt, H.M. (2003) Toxoplasmosis in HIV/AIDS patients in Malaysia. Southeast Asian Journal of Tropical Medicine and Public Health, 57 (2). 18.9. ISSN 0125-1562, |
| spellingShingle | R Medicine Nissapatorn, V. Lee, C.K.C. Cho, S.M. Rohela, M. Anuar, A.K. Quek, K.F. Latt, H.M. Toxoplasmosis in HIV/AIDS patients in Malaysia |
| title | Toxoplasmosis in HIV/AIDS patients in Malaysia |
| title_full | Toxoplasmosis in HIV/AIDS patients in Malaysia |
| title_fullStr | Toxoplasmosis in HIV/AIDS patients in Malaysia |
| title_full_unstemmed | Toxoplasmosis in HIV/AIDS patients in Malaysia |
| title_short | Toxoplasmosis in HIV/AIDS patients in Malaysia |
| title_sort | toxoplasmosis in hiv aids patients in malaysia |
| topic | R Medicine |
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