The role of worm infestation in allergic rhinitis
The purpose of this study is to determine the relevance of the hygiene hypothesis; that is to determine if worm infestation has a protective role against the development of allergic rhinitis. A prospective case controlled study was conducted. Specific IgG levels to Toxocara were studied in 85 patien...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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2012
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| Online Access: | http://eprints.um.edu.my/9387/1/The_role_of_worm_infestation_in_allergic_rhinitis.pdf |
| _version_ | 1825719699776733184 |
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| author | Manuel, A.M. Kuljit, S. Gopalakrishnan, G. Suresh, K.G. Balraj, P. |
| author_facet | Manuel, A.M. Kuljit, S. Gopalakrishnan, G. Suresh, K.G. Balraj, P. |
| author_sort | Manuel, A.M. |
| collection | UM |
| description | The purpose of this study is to determine the relevance of the hygiene hypothesis; that is to determine if worm infestation has a protective role against the development of allergic rhinitis. A prospective case controlled study was conducted. Specific IgG levels to Toxocara were studied in 85 patients confirmed to have allergic rhinitis and were compared to levels in another 85 controls, with no form of allergy. The IgG assay was done using ELISA technique. There was a higher incidence of positive specific IgG to Toxocara in the controls as compared to allergic patients. The values were statistically significant Chi square test (p=0.002). This negative association between worm infestation and allergic rhinitis suggests that a previous worm infestation could protect against the development of allergic rhinitis. |
| first_indexed | 2024-03-06T05:23:44Z |
| format | Article |
| id | um.eprints-9387 |
| institution | Universiti Malaya |
| language | English |
| last_indexed | 2024-03-06T05:23:44Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | um.eprints-93872014-02-17T08:23:37Z http://eprints.um.edu.my/9387/ The role of worm infestation in allergic rhinitis Manuel, A.M. Kuljit, S. Gopalakrishnan, G. Suresh, K.G. Balraj, P. R Medicine The purpose of this study is to determine the relevance of the hygiene hypothesis; that is to determine if worm infestation has a protective role against the development of allergic rhinitis. A prospective case controlled study was conducted. Specific IgG levels to Toxocara were studied in 85 patients confirmed to have allergic rhinitis and were compared to levels in another 85 controls, with no form of allergy. The IgG assay was done using ELISA technique. There was a higher incidence of positive specific IgG to Toxocara in the controls as compared to allergic patients. The values were statistically significant Chi square test (p=0.002). This negative association between worm infestation and allergic rhinitis suggests that a previous worm infestation could protect against the development of allergic rhinitis. 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/9387/1/The_role_of_worm_infestation_in_allergic_rhinitis.pdf Manuel, A.M. and Kuljit, S. and Gopalakrishnan, G. and Suresh, K.G. and Balraj, P. (2012) The role of worm infestation in allergic rhinitis. Tropical Biomedicine, 29 (3). pp. 360-365. ISSN 0127-5720, http://www.ncbi.nlm.nih.gov/pubmed/23018498 |
| spellingShingle | R Medicine Manuel, A.M. Kuljit, S. Gopalakrishnan, G. Suresh, K.G. Balraj, P. The role of worm infestation in allergic rhinitis |
| title | The role of worm infestation in allergic rhinitis |
| title_full | The role of worm infestation in allergic rhinitis |
| title_fullStr | The role of worm infestation in allergic rhinitis |
| title_full_unstemmed | The role of worm infestation in allergic rhinitis |
| title_short | The role of worm infestation in allergic rhinitis |
| title_sort | role of worm infestation in allergic rhinitis |
| topic | R Medicine |
| url | http://eprints.um.edu.my/9387/1/The_role_of_worm_infestation_in_allergic_rhinitis.pdf |
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