The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds

The present study was conducted to fabricate a 3D scaffold using polycaprolactone (PCL) and silicate based bioactive glass-ceramic (R-SBgC). Different concentrations of R-SBgC prepared from rice husk ash (RHA) were combined with PCL to fabricate a composite scaffold using thermally induced phase sep...

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Main Authors: Naghizadeh, F., Sultana, N., Kadir, M.R.A., Shihabudin, T.M.T.M., Hussain, R., Kamarul, Tunku
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2014
Subjects:
Online Access:http://eprints.um.edu.my/9860/1/Naghizadeh-2014-The_Fabrication_and.pdf
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author Naghizadeh, F.
Sultana, N.
Kadir, M.R.A.
Shihabudin, T.M.T.M.
Hussain, R.
Kamarul, Tunku
author_facet Naghizadeh, F.
Sultana, N.
Kadir, M.R.A.
Shihabudin, T.M.T.M.
Hussain, R.
Kamarul, Tunku
author_sort Naghizadeh, F.
collection UM
description The present study was conducted to fabricate a 3D scaffold using polycaprolactone (PCL) and silicate based bioactive glass-ceramic (R-SBgC). Different concentrations of R-SBgC prepared from rice husk ash (RHA) were combined with PCL to fabricate a composite scaffold using thermally induced phase separation (TIPS) method. The products were then characterized using SEM and EDX. The results demonstrated that R-SBgC in PCL matrix produced a bioactive material which has highly porous structure with interconnected porosities. There appears to be a relationship between the increase in R-SBgC concentration and increased material density and compressive modulus; however, increasing R-SBgC concentration result in reduced scaffold porosity. In conclusion, it is possible to fabricate a PCL/bioactive glass-ceramic composite from processed rice husk. Varying the R-SBgC concentrations can control the properties of this material, which is useful in the development of the ideal scaffold intended for use as a bone substitute in nonload bearing sites.
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spelling um.eprints-98602018-10-10T08:59:55Z http://eprints.um.edu.my/9860/ The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds Naghizadeh, F. Sultana, N. Kadir, M.R.A. Shihabudin, T.M.T.M. Hussain, R. Kamarul, Tunku R Medicine The present study was conducted to fabricate a 3D scaffold using polycaprolactone (PCL) and silicate based bioactive glass-ceramic (R-SBgC). Different concentrations of R-SBgC prepared from rice husk ash (RHA) were combined with PCL to fabricate a composite scaffold using thermally induced phase separation (TIPS) method. The products were then characterized using SEM and EDX. The results demonstrated that R-SBgC in PCL matrix produced a bioactive material which has highly porous structure with interconnected porosities. There appears to be a relationship between the increase in R-SBgC concentration and increased material density and compressive modulus; however, increasing R-SBgC concentration result in reduced scaffold porosity. In conclusion, it is possible to fabricate a PCL/bioactive glass-ceramic composite from processed rice husk. Varying the R-SBgC concentrations can control the properties of this material, which is useful in the development of the ideal scaffold intended for use as a bone substitute in nonload bearing sites. Hindawi Publishing Corporation 2014 Article PeerReviewed application/pdf en http://eprints.um.edu.my/9860/1/Naghizadeh-2014-The_Fabrication_and.pdf Naghizadeh, F. and Sultana, N. and Kadir, M.R.A. and Shihabudin, T.M.T.M. and Hussain, R. and Kamarul, Tunku (2014) The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds. Journal of Nanomaterials (JNM), 2014 (2014). ISSN 1687-4110, DOI https://doi.org/10.1155/2014/253185 <https://doi.org/10.1155/2014/253185>. http://www.hindawi.com/journals/jnm/2014/253185/abs/ 10.1155/2014/253185
spellingShingle R Medicine
Naghizadeh, F.
Sultana, N.
Kadir, M.R.A.
Shihabudin, T.M.T.M.
Hussain, R.
Kamarul, Tunku
The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds
title The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds
title_full The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds
title_fullStr The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds
title_full_unstemmed The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds
title_short The Fabrication and Characterization of PCL/Rice husk derived bioactive glass-ceramic composite scaffolds
title_sort fabrication and characterization of pcl rice husk derived bioactive glass ceramic composite scaffolds
topic R Medicine
url http://eprints.um.edu.my/9860/1/Naghizadeh-2014-The_Fabrication_and.pdf
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