| Summary: | Bioactive glasses are biocompatible materials which have been extensively
investigated for development and advancement of tissue engineering and medical
implantation. There are various kind of bioactive glasses and many different
pathways for the production. Sol-gel preparation of 58S and 77S bioactive glasses
had been chosen for this study. These two 585 and 775 bioactive glasses consist of
different percentage of compositions in SiO₂CaO-P₂0s system. Besides investigated
the preparation of bioactive glasses, this study was focused on the effect of different
temperature used in thermal treatment on the bioactivity of bioactive glasses. After
accurate amount of the precursors were added, Decon® surfactant was added to
foam the sol obtained. The foamed gel is then aged, dried and calcinated under
suitable temperature and period. Simulated body fluid was used to represent the
body fluid for the in-vitro study of bioactivity of produced bioactive glasses. The formation of hydroxycarbonate apatite clusters or layer on the surface of bioactive glasses indicated that the produced bioactive glasses was eligible for the tissue
growth. From this study, it was found that after immersion of simulated body fluid
solution, the intensity of hydroxycarbonate apatite clusters formed on the 600°C
calcinated bioactive glasses was higher as compared to the other calcinated bioactive
glasses. Hence, the most optimal calcination temperature for 58S and 77S bioactive
glasses was 600°C.
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