Breast cancer: detection markers, prognosis, and prevention

Breast cancer is the common invasive cancer with high mortality worldwide. High incidence of breast cancer in South and central America, Southren, Northren, Westren Europe, Ocenia and North America. Lowest breast cancer incidence in Africa and Asia. Risk factors includes: female sex old age, lifesty...

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Main Authors: Murtaza Mustafa, A Nornazirah, FA. Salih, EL. Illzam, Monica Suleiman, AM. Sharifa
Format: Article
Language:English
English
Published: International Organization of Scientific Research 2016
Online Access:https://eprints.ums.edu.my/id/eprint/19057/1/Breast%20cancer.pdf
https://eprints.ums.edu.my/id/eprint/19057/7/Breast%20Cancer%20Detection%20Markers%2C%20Prognosis%2C%20and%20Prevention.pdf
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author Murtaza Mustafa
A Nornazirah
FA. Salih
EL. Illzam
Monica Suleiman
AM. Sharifa
author_facet Murtaza Mustafa
A Nornazirah
FA. Salih
EL. Illzam
Monica Suleiman
AM. Sharifa
author_sort Murtaza Mustafa
collection UMS
description Breast cancer is the common invasive cancer with high mortality worldwide. High incidence of breast cancer in South and central America, Southren, Northren, Westren Europe, Ocenia and North America. Lowest breast cancer incidence in Africa and Asia. Risk factors includes: female sex old age, lifestyle, oralcontraceptive, hormone replacement therapy, mutations in the breast cancer susceptibility genes BRCA1orBRCA2.alcohol intake, hereditary factors, and exposure to chemicals. Breast cancer occurs because of an interaction between external factor and genetically susceptible host. Frequent symptoms of breast cancer is typically a lump and lumps found in the lymph node in the armpits. Diagnosis by physical examination of the breast and mammography. Further tests include histopathological examination, breast cells grading by TNM systeme.g., Zero stage a precancerous or marker condition, stage 1- 3 within the breast and regional nodes, and stage four is metastatic stage. Management of breast cancer depends on the stage of the cancer and age of the patient. Usually treated with surgery, chemotherapy or radiation therapy or both. A multidisciplinary approach is preferable. Metastatic cancer has less favorable prognosis. Prognosis is usually the probability of progression-free survival(PFS) or disease free survival(DFS).Prevention include change in life style, maintaining healthy weight, less alcohol consumption, and intake of marine omega-3 and soy-based foods Prophylactic mastectomy(removal of both breasts) helps in people with BRCA1 and BRCA2 mutations. Early detection of breast cancer has better prognosis.
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spelling ums.eprints-190572020-12-28T04:35:58Z https://eprints.ums.edu.my/id/eprint/19057/ Breast cancer: detection markers, prognosis, and prevention Murtaza Mustafa A Nornazirah FA. Salih EL. Illzam Monica Suleiman AM. Sharifa Breast cancer is the common invasive cancer with high mortality worldwide. High incidence of breast cancer in South and central America, Southren, Northren, Westren Europe, Ocenia and North America. Lowest breast cancer incidence in Africa and Asia. Risk factors includes: female sex old age, lifestyle, oralcontraceptive, hormone replacement therapy, mutations in the breast cancer susceptibility genes BRCA1orBRCA2.alcohol intake, hereditary factors, and exposure to chemicals. Breast cancer occurs because of an interaction between external factor and genetically susceptible host. Frequent symptoms of breast cancer is typically a lump and lumps found in the lymph node in the armpits. Diagnosis by physical examination of the breast and mammography. Further tests include histopathological examination, breast cells grading by TNM systeme.g., Zero stage a precancerous or marker condition, stage 1- 3 within the breast and regional nodes, and stage four is metastatic stage. Management of breast cancer depends on the stage of the cancer and age of the patient. Usually treated with surgery, chemotherapy or radiation therapy or both. A multidisciplinary approach is preferable. Metastatic cancer has less favorable prognosis. Prognosis is usually the probability of progression-free survival(PFS) or disease free survival(DFS).Prevention include change in life style, maintaining healthy weight, less alcohol consumption, and intake of marine omega-3 and soy-based foods Prophylactic mastectomy(removal of both breasts) helps in people with BRCA1 and BRCA2 mutations. Early detection of breast cancer has better prognosis. International Organization of Scientific Research 2016-08 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/19057/1/Breast%20cancer.pdf text en https://eprints.ums.edu.my/id/eprint/19057/7/Breast%20Cancer%20Detection%20Markers%2C%20Prognosis%2C%20and%20Prevention.pdf Murtaza Mustafa and A Nornazirah and FA. Salih and EL. Illzam and Monica Suleiman and AM. Sharifa (2016) Breast cancer: detection markers, prognosis, and prevention. IOSR Journal of Dental and Medical Sciences, 15 (8). pp. 73-80. ISSN 2279-0853 http://doi.org/10.9790/0853-1508117380
spellingShingle Murtaza Mustafa
A Nornazirah
FA. Salih
EL. Illzam
Monica Suleiman
AM. Sharifa
Breast cancer: detection markers, prognosis, and prevention
title Breast cancer: detection markers, prognosis, and prevention
title_full Breast cancer: detection markers, prognosis, and prevention
title_fullStr Breast cancer: detection markers, prognosis, and prevention
title_full_unstemmed Breast cancer: detection markers, prognosis, and prevention
title_short Breast cancer: detection markers, prognosis, and prevention
title_sort breast cancer detection markers prognosis and prevention
url https://eprints.ums.edu.my/id/eprint/19057/1/Breast%20cancer.pdf
https://eprints.ums.edu.my/id/eprint/19057/7/Breast%20Cancer%20Detection%20Markers%2C%20Prognosis%2C%20and%20Prevention.pdf
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