Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef
This study was carried out on 5 Laurencia species. They are Laurencia snackeyi, Laurencia nangii, Laurencia sp., Laurencia papilose, and Laurencia cribb. Five halogenated secondary metabolites were isolated from L. snackeyi. The halogenated secondary metabolites are (2Z., 6S·, 9R·)-chamigr-2, 5(I4)-...
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| Format: | Academic Exercise |
| Language: | English |
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2006
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| Online Access: | https://eprints.ums.edu.my/id/eprint/20131/1/Chemical%20diversity%20and%20biological%20activities%20of%20Halogenated%20metabolites%20from%20Red%20Algae%20Genus%20Laurencia%20from%20Carrington%20Reef..pdf |
| _version_ | 1825713469585883136 |
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| author | Toh, Denise Yew Leng |
| author_facet | Toh, Denise Yew Leng |
| author_sort | Toh, Denise Yew Leng |
| collection | UMS |
| description | This study was carried out on 5 Laurencia species. They are Laurencia snackeyi, Laurencia nangii, Laurencia sp., Laurencia papilose, and Laurencia cribb. Five halogenated secondary metabolites were isolated from L. snackeyi. The halogenated secondary metabolites are (2Z., 6S·, 9R·)-chamigr-2, 5(I4)-dien-8-one (80), Palisadin B (76), 5-acetoxypalisadin B (7), Aplysistatin (6), and 5f3-hydroxypalisadin B (81). The halogenated secondary metabolites were then tested against marine environmental bacteria, human pathogenic bacteria and yeast. (2Z., 6S·, 9R·)chamigr- 2, 5(l4)-dien-8-one (80) and Palisadin B (76) did not show any positive activity against aU of them 5-acetoxypalisadin B (7) and Aplysistatin (6) showed
positive activity against 5 marine environmental bacteria which were Clostridium cellobioparum, Clostridium sordelli, Clostridium novyi, Vibrio arginolyticus and Vibrio parahaemolyticus. 5f3-hydroxypalisadin B (81) showed positive activity against 2 marine environmental bacteria which were Clostridium sordelli and Vibrio parahaemolyticus, 2 human pathogenic bacteria Vibrio chlolera and E. coli, and 2 different strains of Candida albicans yeast. |
| first_indexed | 2024-03-06T02:57:05Z |
| format | Academic Exercise |
| id | ums.eprints-20131 |
| institution | Universiti Malaysia Sabah |
| language | English |
| last_indexed | 2024-03-06T02:57:05Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | ums.eprints-201312018-06-04T00:18:06Z https://eprints.ums.edu.my/id/eprint/20131/ Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef Toh, Denise Yew Leng QH Natural history This study was carried out on 5 Laurencia species. They are Laurencia snackeyi, Laurencia nangii, Laurencia sp., Laurencia papilose, and Laurencia cribb. Five halogenated secondary metabolites were isolated from L. snackeyi. The halogenated secondary metabolites are (2Z., 6S·, 9R·)-chamigr-2, 5(I4)-dien-8-one (80), Palisadin B (76), 5-acetoxypalisadin B (7), Aplysistatin (6), and 5f3-hydroxypalisadin B (81). The halogenated secondary metabolites were then tested against marine environmental bacteria, human pathogenic bacteria and yeast. (2Z., 6S·, 9R·)chamigr- 2, 5(l4)-dien-8-one (80) and Palisadin B (76) did not show any positive activity against aU of them 5-acetoxypalisadin B (7) and Aplysistatin (6) showed positive activity against 5 marine environmental bacteria which were Clostridium cellobioparum, Clostridium sordelli, Clostridium novyi, Vibrio arginolyticus and Vibrio parahaemolyticus. 5f3-hydroxypalisadin B (81) showed positive activity against 2 marine environmental bacteria which were Clostridium sordelli and Vibrio parahaemolyticus, 2 human pathogenic bacteria Vibrio chlolera and E. coli, and 2 different strains of Candida albicans yeast. 2006 Academic Exercise NonPeerReviewed text en https://eprints.ums.edu.my/id/eprint/20131/1/Chemical%20diversity%20and%20biological%20activities%20of%20Halogenated%20metabolites%20from%20Red%20Algae%20Genus%20Laurencia%20from%20Carrington%20Reef..pdf Toh, Denise Yew Leng (2006) Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef. Universiti Malaysia Sabah. (Unpublished) |
| spellingShingle | QH Natural history Toh, Denise Yew Leng Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef |
| title | Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef |
| title_full | Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef |
| title_fullStr | Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef |
| title_full_unstemmed | Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef |
| title_short | Chemical diversity and biological activities of Halogenated metabolites from Red Algae Genus Laurencia from Carrington Reef |
| title_sort | chemical diversity and biological activities of halogenated metabolites from red algae genus laurencia from carrington reef |
| topic | QH Natural history |
| url | https://eprints.ums.edu.my/id/eprint/20131/1/Chemical%20diversity%20and%20biological%20activities%20of%20Halogenated%20metabolites%20from%20Red%20Algae%20Genus%20Laurencia%20from%20Carrington%20Reef..pdf |
| work_keys_str_mv | AT tohdeniseyewleng chemicaldiversityandbiologicalactivitiesofhalogenatedmetabolitesfromredalgaegenuslaurenciafromcarringtonreef |