Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction
Subcritical carbon dioxide Soxhlet extraction of biologically active compounds from Clincanthus nutans was investigated by full factorial design to identify and optimize the factors (particle size and co-solvent) affecting extract yield, antioxidant activity, total phenolic content, total flavonoid...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2017
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| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/20632/1/Identification%20of%20bioactive%20compounds%20with%20GC.pdf |
| _version_ | 1796910018442821632 |
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| author | Md Ariful Alam Md Zaidul Islam Sarker Kashif Ghafoor Sahena Ferdosh Md. Eaqub Ali Hamed Mirhosseini Kamaruzzaman Yunus Md Jahurul Haque Akanda A. Khatib |
| author_facet | Md Ariful Alam Md Zaidul Islam Sarker Kashif Ghafoor Sahena Ferdosh Md. Eaqub Ali Hamed Mirhosseini Kamaruzzaman Yunus Md Jahurul Haque Akanda A. Khatib |
| author_sort | Md Ariful Alam |
| collection | UMS |
| description | Subcritical carbon dioxide Soxhlet extraction of biologically active compounds from Clincanthus nutans was investigated by full factorial design to identify and optimize the factors (particle size and co-solvent) affecting extract yield, antioxidant activity, total phenolic content, total flavonoid content, and α-glucosidase inhibitory activity. An average of 3.103% yield, 98.90% antioxidant activity, 49.40 mg/g (GAE) TPC, 43.76 mg/g (RE), and 88.58% AGI activity can be achieved using the optimum levels of independent variables. The GC-Q-TOF MS identification of optimized extract shown that different classes of phytoconstituents were successfully separated by CO2-Soxhlet to produce potential antioxidant and α-glucosidase inhibitory activity. |
| first_indexed | 2024-03-06T02:58:12Z |
| format | Article |
| id | ums.eprints-20632 |
| institution | Universiti Malaysia Sabah |
| language | English |
| last_indexed | 2024-03-06T02:58:12Z |
| publishDate | 2017 |
| publisher | Taylor & Francis Group |
| record_format | dspace |
| spelling | ums.eprints-206322018-08-03T02:59:26Z https://eprints.ums.edu.my/id/eprint/20632/ Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction Md Ariful Alam Md Zaidul Islam Sarker Kashif Ghafoor Sahena Ferdosh Md. Eaqub Ali Hamed Mirhosseini Kamaruzzaman Yunus Md Jahurul Haque Akanda A. Khatib QK Botany Subcritical carbon dioxide Soxhlet extraction of biologically active compounds from Clincanthus nutans was investigated by full factorial design to identify and optimize the factors (particle size and co-solvent) affecting extract yield, antioxidant activity, total phenolic content, total flavonoid content, and α-glucosidase inhibitory activity. An average of 3.103% yield, 98.90% antioxidant activity, 49.40 mg/g (GAE) TPC, 43.76 mg/g (RE), and 88.58% AGI activity can be achieved using the optimum levels of independent variables. The GC-Q-TOF MS identification of optimized extract shown that different classes of phytoconstituents were successfully separated by CO2-Soxhlet to produce potential antioxidant and α-glucosidase inhibitory activity. Taylor & Francis Group 2017 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/20632/1/Identification%20of%20bioactive%20compounds%20with%20GC.pdf Md Ariful Alam and Md Zaidul Islam Sarker and Kashif Ghafoor and Sahena Ferdosh and Md. Eaqub Ali and Hamed Mirhosseini and Kamaruzzaman Yunus and Md Jahurul Haque Akanda and A. Khatib (2017) Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction. Separation Science and Technology, 52 (5). pp. 852-863. ISSN 1520-5754 https://doi.org/10.1080/01496395.2016.1271342 |
| spellingShingle | QK Botany Md Ariful Alam Md Zaidul Islam Sarker Kashif Ghafoor Sahena Ferdosh Md. Eaqub Ali Hamed Mirhosseini Kamaruzzaman Yunus Md Jahurul Haque Akanda A. Khatib Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction |
| title | Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction |
| title_full | Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction |
| title_fullStr | Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction |
| title_full_unstemmed | Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction |
| title_short | Identification of bioactive compounds with GC–Q-TOF–MS in the extracts from Clinacanthus nutans using subcritical carbon dioxide extraction |
| title_sort | identification of bioactive compounds with gc q tof ms in the extracts from clinacanthus nutans using subcritical carbon dioxide extraction |
| topic | QK Botany |
| url | https://eprints.ums.edu.my/id/eprint/20632/1/Identification%20of%20bioactive%20compounds%20with%20GC.pdf |
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