Aims Increased expression of senescence markers p14ARF and p16INK4a in breast cancer is associated with an increased risk of disease recurrence and poor survival outcome
Breast cancer is a hormonally driven disease. Cellular senescence is an age‐related irreversible cell cycle arrest at the G1 phase upon induction. The aim of this study was to characterize the expression patterns of the senescence markers p14ARF, p16INK4a and p21WAF1/Cip1 during breast cancer progre...
Main Authors: | Rahmawati Pare, Joo, Shik Shin, Cheok, Soon Lee |
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Format: | Article |
Language: | English |
Published: |
John Wiley & Sons, Inc.
2016
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Subjects: | |
Online Access: | https://eprints.ums.edu.my/id/eprint/21488/1/Increased%20expression%20of%20senescence%20markers%20p14ARF%20and%20p16INK4a%20in%20breast%20cancer%20is%20associated%20with%20an%20increased%20risk%20of%20disease%20recurrence%20and%20poor%20survival%20outcome.pdf |
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