Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis
Background: A slight increase in the childhood cancer trend has been observed for the past few decades. Non-ionizing radiation is one of the environmental factors linked to childhood cancers. This review is conducted to assess the association between non-ionizing radiation and childhood cancer based...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
2020
|
| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/25095/7/Exposure%20to%20Non-Ionizing%20Radiation%20and%20Childhood%20Cancer_A%20Meta-Analysis.pdf |
| _version_ | 1796910329335119872 |
|---|---|
| author | Aznida Mohamad Zaki Muhammad Aklil Abd Rahim Zuraidah Zaidun Abdul Rahman Ramdzan Zaleha Md Isa |
| author_facet | Aznida Mohamad Zaki Muhammad Aklil Abd Rahim Zuraidah Zaidun Abdul Rahman Ramdzan Zaleha Md Isa |
| author_sort | Aznida Mohamad Zaki |
| collection | UMS |
| description | Background: A slight increase in the childhood cancer trend has been observed for the past few decades. Non-ionizing radiation is one of the environmental factors linked to childhood cancers. This review is conducted to assess the association between non-ionizing radiation and childhood cancer based on all original studies to date.
Methods: A systematic search was conducted on the titles and abstracts pertaining to non-ionizing radiation and childhood cancers using the PubMed, Scopus, SAGE and ScienceDirect databases from inception up to November 2018. Quality of each article was appraised using the Newcastle-Ottawa Scale, meta-analysis was performed with Review Manager, and fixed effects were used to estimate the pooled OR of the selected studies.
Results: A total of 15 articles met all the selection criteria. Twelve articles were included in the meta-analysis. Pooled risk estimates of the 12 studies, obtained via fixed effects model, showed that children exposed to 0.2 µT or more of EMF non-ionizing radiation run 1.33 times higher risks of contracting childhood cancer compared to those with less than 0.2 µT exposure (95% CI: 1.10, 1.60). The studies were statistically homogeneous (chi-squared P=0.71, I2=0%), and there was no evidence of publication bias.
Conclusion: It cannot be concluded that children exposed to non-ionizing radiation have higher risks of childhood cancer compared to those who were not exposed as claimed by the previous reviews. However, concerns about non-ionizing radiation exposure and childhood cancer should not be neglected. |
| first_indexed | 2024-03-06T03:02:51Z |
| format | Article |
| id | ums.eprints-25095 |
| institution | Universiti Malaysia Sabah |
| language | English |
| last_indexed | 2024-03-06T03:02:51Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ums.eprints-250952020-04-16T15:37:49Z https://eprints.ums.edu.my/id/eprint/25095/ Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis Aznida Mohamad Zaki Muhammad Aklil Abd Rahim Zuraidah Zaidun Abdul Rahman Ramdzan Zaleha Md Isa R Medicine (General) RC Internal medicine Background: A slight increase in the childhood cancer trend has been observed for the past few decades. Non-ionizing radiation is one of the environmental factors linked to childhood cancers. This review is conducted to assess the association between non-ionizing radiation and childhood cancer based on all original studies to date. Methods: A systematic search was conducted on the titles and abstracts pertaining to non-ionizing radiation and childhood cancers using the PubMed, Scopus, SAGE and ScienceDirect databases from inception up to November 2018. Quality of each article was appraised using the Newcastle-Ottawa Scale, meta-analysis was performed with Review Manager, and fixed effects were used to estimate the pooled OR of the selected studies. Results: A total of 15 articles met all the selection criteria. Twelve articles were included in the meta-analysis. Pooled risk estimates of the 12 studies, obtained via fixed effects model, showed that children exposed to 0.2 µT or more of EMF non-ionizing radiation run 1.33 times higher risks of contracting childhood cancer compared to those with less than 0.2 µT exposure (95% CI: 1.10, 1.60). The studies were statistically homogeneous (chi-squared P=0.71, I2=0%), and there was no evidence of publication bias. Conclusion: It cannot be concluded that children exposed to non-ionizing radiation have higher risks of childhood cancer compared to those who were not exposed as claimed by the previous reviews. However, concerns about non-ionizing radiation exposure and childhood cancer should not be neglected. 2020-01 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/25095/7/Exposure%20to%20Non-Ionizing%20Radiation%20and%20Childhood%20Cancer_A%20Meta-Analysis.pdf Aznida Mohamad Zaki and Muhammad Aklil Abd Rahim and Zuraidah Zaidun and Abdul Rahman Ramdzan and Zaleha Md Isa (2020) Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis. Middle East Journal of Cancer, 11 (1). pp. 1-11. |
| spellingShingle | R Medicine (General) RC Internal medicine Aznida Mohamad Zaki Muhammad Aklil Abd Rahim Zuraidah Zaidun Abdul Rahman Ramdzan Zaleha Md Isa Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis |
| title | Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis |
| title_full | Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis |
| title_fullStr | Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis |
| title_full_unstemmed | Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis |
| title_short | Exposure to Non-Ionizing Radiation and Childhood Cancer: A Meta-Analysis |
| title_sort | exposure to non ionizing radiation and childhood cancer a meta analysis |
| topic | R Medicine (General) RC Internal medicine |
| url | https://eprints.ums.edu.my/id/eprint/25095/7/Exposure%20to%20Non-Ionizing%20Radiation%20and%20Childhood%20Cancer_A%20Meta-Analysis.pdf |
| work_keys_str_mv | AT aznidamohamadzaki exposuretononionizingradiationandchildhoodcancerametaanalysis AT muhammadaklilabdrahim exposuretononionizingradiationandchildhoodcancerametaanalysis AT zuraidahzaidun exposuretononionizingradiationandchildhoodcancerametaanalysis AT abdulrahmanramdzan exposuretononionizingradiationandchildhoodcancerametaanalysis AT zalehamdisa exposuretononionizingradiationandchildhoodcancerametaanalysis |