Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia
Pregnant women with high blood lead posed high risk to their fetus as placental transfer can occurs to the fetus. The objective of this study was to identify the relationship between blood lead and the neuropsychological score of women who were in their 3rd trimester of pregnancy. These responde...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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IJMLST
2020
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| Online Access: | https://eprints.ums.edu.my/id/eprint/25328/1/Blood%20Lead%20Concentrations%20and%20The%20Neuropsychology%20Scores%20of%20Pregnant%20Women%20in%20Klang%20Valley%20Malaysia.pdf |
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| author | Shamsul Bahari Shamsudin Jamal Hisham Hashim Nik Nasri Nik Ismail A. Jamal A. Rahman Maharani Pertiwi Koentjoro |
| author_facet | Shamsul Bahari Shamsudin Jamal Hisham Hashim Nik Nasri Nik Ismail A. Jamal A. Rahman Maharani Pertiwi Koentjoro |
| author_sort | Shamsul Bahari Shamsudin |
| collection | UMS |
| description | Pregnant women with high blood lead posed high risk to
their fetus as placental transfer can occurs to the fetus. The objective of this study was to identify the relationship
between blood lead and the neuropsychological score of
women who were in their 3rd trimester of pregnancy. These
respondents were undergoing a routine antenatal checkup at
a teaching hospital located in Klang Valley areas. Blood
lead concentrations were analyzed using graphite furnace
Atomic Absorption Spectrophotometer (AAS). The
neuropsychological scores were measured with WHO
Neurobehavioral Core Test battery (NCTB). The test
consists of 7 items, which made up of the Digit Symbol,
Trail Making, Digit Span, Benton Visual Retention Test,
Pursuit Aiming, Santa Ana Manual Dexterity, Reaction
Time and Movement Time tests. The mean blood lead was
7.78±4.77 µg/dL. The mean score for the total NCTB test
was 50.00±5.24. Statistical analysis showed blood lead
concentrations were inversely correlated with the total
NCTB score (r= –0.462, p≤0.01). The correlation was about
21.3%. The General Linear Model (GLM) showed that age
(β= –0.15, p=0.017), weight (β=2.67, p=0.05) and height
(β=–1.97, p=0.05) also influence the total
neuropsychological scores. In conclusion, blood lead
reduces the total neuropsychological scores. The scores for
each of the 7 items were inversely and significantly
correlated with blood lead concentrations except for the
Trail Making and Santa Ana Manual Dexterity tests. |
| first_indexed | 2024-03-06T03:03:21Z |
| format | Article |
| id | ums.eprints-25328 |
| institution | Universiti Malaysia Sabah |
| language | English |
| last_indexed | 2024-03-06T03:03:21Z |
| publishDate | 2020 |
| publisher | IJMLST |
| record_format | dspace |
| spelling | ums.eprints-253282020-04-20T03:28:29Z https://eprints.ums.edu.my/id/eprint/25328/ Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia Shamsul Bahari Shamsudin Jamal Hisham Hashim Nik Nasri Nik Ismail A. Jamal A. Rahman Maharani Pertiwi Koentjoro R Medicine (General) Pregnant women with high blood lead posed high risk to their fetus as placental transfer can occurs to the fetus. The objective of this study was to identify the relationship between blood lead and the neuropsychological score of women who were in their 3rd trimester of pregnancy. These respondents were undergoing a routine antenatal checkup at a teaching hospital located in Klang Valley areas. Blood lead concentrations were analyzed using graphite furnace Atomic Absorption Spectrophotometer (AAS). The neuropsychological scores were measured with WHO Neurobehavioral Core Test battery (NCTB). The test consists of 7 items, which made up of the Digit Symbol, Trail Making, Digit Span, Benton Visual Retention Test, Pursuit Aiming, Santa Ana Manual Dexterity, Reaction Time and Movement Time tests. The mean blood lead was 7.78±4.77 µg/dL. The mean score for the total NCTB test was 50.00±5.24. Statistical analysis showed blood lead concentrations were inversely correlated with the total NCTB score (r= –0.462, p≤0.01). The correlation was about 21.3%. The General Linear Model (GLM) showed that age (β= –0.15, p=0.017), weight (β=2.67, p=0.05) and height (β=–1.97, p=0.05) also influence the total neuropsychological scores. In conclusion, blood lead reduces the total neuropsychological scores. The scores for each of the 7 items were inversely and significantly correlated with blood lead concentrations except for the Trail Making and Santa Ana Manual Dexterity tests. IJMLST 2020 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/25328/1/Blood%20Lead%20Concentrations%20and%20The%20Neuropsychology%20Scores%20of%20Pregnant%20Women%20in%20Klang%20Valley%20Malaysia.pdf Shamsul Bahari Shamsudin and Jamal Hisham Hashim and Nik Nasri Nik Ismail and A. Jamal A. Rahman and Maharani Pertiwi Koentjoro (2020) Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia. Indonesian Journal of Medical Laboratory Science and Technology, 2 (1). pp. 11-20. ISSN 2656-9825 https://doi.org/10.33086/ijmlst.v2i1.1499 |
| spellingShingle | R Medicine (General) Shamsul Bahari Shamsudin Jamal Hisham Hashim Nik Nasri Nik Ismail A. Jamal A. Rahman Maharani Pertiwi Koentjoro Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia |
| title | Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia |
| title_full | Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia |
| title_fullStr | Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia |
| title_full_unstemmed | Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia |
| title_short | Blood lead concentrations and the Neuropsychology scores of pregnant women in Klang Valley Malaysia |
| title_sort | blood lead concentrations and the neuropsychology scores of pregnant women in klang valley malaysia |
| topic | R Medicine (General) |
| url | https://eprints.ums.edu.my/id/eprint/25328/1/Blood%20Lead%20Concentrations%20and%20The%20Neuropsychology%20Scores%20of%20Pregnant%20Women%20in%20Klang%20Valley%20Malaysia.pdf |
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