Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life
Purpose To evaluate if and how post-traumatic brain injury (TBI) olfactory dysfunction affects the quality of life (QoL). Methods In this case–control observational study, 32 adults with post-TBI olfactory dysfunction (cases) were matched with 32 TBI patients with intact olfactory function (con...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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2020
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| Online Access: | https://eprints.ums.edu.my/id/eprint/25424/1/Post-traumatic%20brain%20injury%20olfactory%20dysfunction%20factors%20influencing%20quality%20of%20life.pdf |
| _version_ | 1796910367813664768 |
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| author | Fatimah Ahmedy Mazlina Mazlan Mahmoud Danaee Mohd Zulkiflee Abu Bakar |
| author_facet | Fatimah Ahmedy Mazlina Mazlan Mahmoud Danaee Mohd Zulkiflee Abu Bakar |
| author_sort | Fatimah Ahmedy |
| collection | UMS |
| description | Purpose
To evaluate if and how post-traumatic brain injury (TBI) olfactory dysfunction affects the quality of life (QoL).
Methods
In this case–control observational study, 32 adults with post-TBI olfactory dysfunction (cases) were matched with 32 TBI patients with intact olfactory function (controls). All subjects self-rated their olfactory function using the Visual Analogue Scale (VAS). Cases also underwent objective olfactory function assessment with the Sniffin’ Sticks test, which generated a Threshold, Discrimination, and Identification (TDI) score. QoL was assessed with the Questionnaire for Olfactory Disorders (QOD). Factors evaluated included age, gender, smoking, TBI severity and duration, lesion localisation, and Disability Rating Scale (DRS) score.
Results
Cases had a higher mean QOD score than controls at 26.31 ± 14.37 and 9.44 ± 8.30, respectively (F = 16.426, p < 0.001, η2 = 0.224). The effect size was large (d = 1.07) with an odds ratio of 7.02. The features of QoL most affected were perception of smell changes, adapting to smell changes, and fear of hazardous substance exposure. DRS score and severity of olfactory dysfunction significantly affected QoL (p < 0.05).
Conclusion
Post-TBI olfactory dysfunction significantly lowered QoL and increased the likelihood of having a low QoL relative to TBI alone. |
| first_indexed | 2024-03-06T03:03:24Z |
| format | Article |
| id | ums.eprints-25424 |
| institution | Universiti Malaysia Sabah |
| language | English |
| last_indexed | 2024-03-06T03:03:24Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | ums.eprints-254242020-05-28T02:28:50Z https://eprints.ums.edu.my/id/eprint/25424/ Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life Fatimah Ahmedy Mazlina Mazlan Mahmoud Danaee Mohd Zulkiflee Abu Bakar RC Internal medicine Purpose To evaluate if and how post-traumatic brain injury (TBI) olfactory dysfunction affects the quality of life (QoL). Methods In this case–control observational study, 32 adults with post-TBI olfactory dysfunction (cases) were matched with 32 TBI patients with intact olfactory function (controls). All subjects self-rated their olfactory function using the Visual Analogue Scale (VAS). Cases also underwent objective olfactory function assessment with the Sniffin’ Sticks test, which generated a Threshold, Discrimination, and Identification (TDI) score. QoL was assessed with the Questionnaire for Olfactory Disorders (QOD). Factors evaluated included age, gender, smoking, TBI severity and duration, lesion localisation, and Disability Rating Scale (DRS) score. Results Cases had a higher mean QOD score than controls at 26.31 ± 14.37 and 9.44 ± 8.30, respectively (F = 16.426, p < 0.001, η2 = 0.224). The effect size was large (d = 1.07) with an odds ratio of 7.02. The features of QoL most affected were perception of smell changes, adapting to smell changes, and fear of hazardous substance exposure. DRS score and severity of olfactory dysfunction significantly affected QoL (p < 0.05). Conclusion Post-TBI olfactory dysfunction significantly lowered QoL and increased the likelihood of having a low QoL relative to TBI alone. 2020 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/25424/1/Post-traumatic%20brain%20injury%20olfactory%20dysfunction%20factors%20influencing%20quality%20of%20life.pdf Fatimah Ahmedy and Mazlina Mazlan and Mahmoud Danaee and Mohd Zulkiflee Abu Bakar (2020) Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life. European Archives of Oto-Rhino-Laryngology, 277. pp. 1343-1351. |
| spellingShingle | RC Internal medicine Fatimah Ahmedy Mazlina Mazlan Mahmoud Danaee Mohd Zulkiflee Abu Bakar Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life |
| title | Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life |
| title_full | Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life |
| title_fullStr | Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life |
| title_full_unstemmed | Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life |
| title_short | Post-traumatic brain injury olfactory dysfunction: factors influencing quality of life |
| title_sort | post traumatic brain injury olfactory dysfunction factors influencing quality of life |
| topic | RC Internal medicine |
| url | https://eprints.ums.edu.my/id/eprint/25424/1/Post-traumatic%20brain%20injury%20olfactory%20dysfunction%20factors%20influencing%20quality%20of%20life.pdf |
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