Cytotoxic sesquiterpenoids from soft coral Capnella imbricata
A new sesquiterpene, capgermacrene H (1) was isolated together with 7 other compounds, capgermacrenes A-G (2-8), from a population of soft coral Capnella imbricata collected from Mantanani Island, Sabah, Malaysia. The structure of this metabolite was elucidated based on spectroscopic data such as nu...
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| Format: | Article |
| Language: | English English |
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2019
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| Online Access: | https://eprints.ums.edu.my/id/eprint/25474/1/Cytotoxic%20sesquiterpenoids%20from%20soft%20coral%20Capnella%20imbricata.pdf https://eprints.ums.edu.my/id/eprint/25474/2/Cytotoxic%20sesquiterpenoids%20from%20soft%20coral%20Capnella%20imbricata%201.pdf |
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| author | Phan, Chin Soon Takashi Kamada Takahiro Ishii Toshiyuki Hamada Charles Santhanaraju Vairappan |
| author_facet | Phan, Chin Soon Takashi Kamada Takahiro Ishii Toshiyuki Hamada Charles Santhanaraju Vairappan |
| author_sort | Phan, Chin Soon |
| collection | UMS |
| description | A new sesquiterpene, capgermacrene H (1) was isolated together with 7 other compounds, capgermacrenes A-G (2-8), from a population of soft coral Capnella imbricata collected from Mantanani Island, Sabah, Malaysia. The structure of this metabolite was elucidated based on spectroscopic data such as nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry. Capgermacrene A (2) showed potent cytotoxicity against adult T-cell leukemia, S1T cells at half-maximal inhibitory concentration of 0.79 µg/mL. |
| first_indexed | 2024-03-06T03:03:29Z |
| format | Article |
| id | ums.eprints-25474 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:03:29Z |
| publishDate | 2019 |
| record_format | dspace |
| spelling | ums.eprints-254742020-06-02T08:55:59Z https://eprints.ums.edu.my/id/eprint/25474/ Cytotoxic sesquiterpenoids from soft coral Capnella imbricata Phan, Chin Soon Takashi Kamada Takahiro Ishii Toshiyuki Hamada Charles Santhanaraju Vairappan SH Aquaculture. Fisheries. Angling A new sesquiterpene, capgermacrene H (1) was isolated together with 7 other compounds, capgermacrenes A-G (2-8), from a population of soft coral Capnella imbricata collected from Mantanani Island, Sabah, Malaysia. The structure of this metabolite was elucidated based on spectroscopic data such as nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry. Capgermacrene A (2) showed potent cytotoxicity against adult T-cell leukemia, S1T cells at half-maximal inhibitory concentration of 0.79 µg/mL. 2019 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/25474/1/Cytotoxic%20sesquiterpenoids%20from%20soft%20coral%20Capnella%20imbricata.pdf text en https://eprints.ums.edu.my/id/eprint/25474/2/Cytotoxic%20sesquiterpenoids%20from%20soft%20coral%20Capnella%20imbricata%201.pdf Phan, Chin Soon and Takashi Kamada and Takahiro Ishii and Toshiyuki Hamada and Charles Santhanaraju Vairappan (2019) Cytotoxic sesquiterpenoids from soft coral Capnella imbricata. Natural Product Communications. pp. 1-4. https://doi.org/10.1177/1934578X19857494 |
| spellingShingle | SH Aquaculture. Fisheries. Angling Phan, Chin Soon Takashi Kamada Takahiro Ishii Toshiyuki Hamada Charles Santhanaraju Vairappan Cytotoxic sesquiterpenoids from soft coral Capnella imbricata |
| title | Cytotoxic sesquiterpenoids from soft coral Capnella imbricata |
| title_full | Cytotoxic sesquiterpenoids from soft coral Capnella imbricata |
| title_fullStr | Cytotoxic sesquiterpenoids from soft coral Capnella imbricata |
| title_full_unstemmed | Cytotoxic sesquiterpenoids from soft coral Capnella imbricata |
| title_short | Cytotoxic sesquiterpenoids from soft coral Capnella imbricata |
| title_sort | cytotoxic sesquiterpenoids from soft coral capnella imbricata |
| topic | SH Aquaculture. Fisheries. Angling |
| url | https://eprints.ums.edu.my/id/eprint/25474/1/Cytotoxic%20sesquiterpenoids%20from%20soft%20coral%20Capnella%20imbricata.pdf https://eprints.ums.edu.my/id/eprint/25474/2/Cytotoxic%20sesquiterpenoids%20from%20soft%20coral%20Capnella%20imbricata%201.pdf |
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