Aaptamine-related alkaloid from the marine sponge Aaptos aaptos
A new aaptamine-related alkaloid, 1,3-dioxolo [4,5-d] benzo [de]-1,6-naphthyridine (methylenedioxyaaptamine, 1), was isolated from the organic extracts of the Bornean marine sponge Aaptos aaptos, together with a known aaptamine derivative, 8,9,9-trimethoxy-9H-benzo [de]-1,6-naphthyridine (2). The st...
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| Format: | Article |
| Language: | English English |
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2019
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| Online Access: | https://eprints.ums.edu.my/id/eprint/25475/1/Aaptamine-related%20alkaloid%20from%20the%20marine%20sponge%20Aaptos%20aaptos.pdf https://eprints.ums.edu.my/id/eprint/25475/2/Aaptamine-related%20alkaloid%20from%20the%20marine%20sponge%20Aaptos%20aaptos%201.pdf |
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| author | Toshiyuki Hamada Yoshito Matsumoto Phan, Chin Soon Takashi Kamada Satoaki Onitsuka Hiroaki Okamura Tetsuo Iwagawa Naomichi Arima Fumito Tani Charles S. Vairappan |
| author_facet | Toshiyuki Hamada Yoshito Matsumoto Phan, Chin Soon Takashi Kamada Satoaki Onitsuka Hiroaki Okamura Tetsuo Iwagawa Naomichi Arima Fumito Tani Charles S. Vairappan |
| author_sort | Toshiyuki Hamada |
| collection | UMS |
| description | A new aaptamine-related alkaloid, 1,3-dioxolo [4,5-d] benzo [de]-1,6-naphthyridine (methylenedioxyaaptamine, 1), was isolated from the organic extracts of the Bornean marine sponge Aaptos aaptos, together with a known aaptamine derivative, 8,9,9-trimethoxy-9H-benzo [de]-1,6-naphthyridine (2). The structure of compound 1 was elucidated by interpretation of its spectroscopic data. Two compounds were tested for their cytotoxic potentials against adult T-cell leukemia (ATL) cells, and compound 1 showed moderate cytotoxic potential. |
| first_indexed | 2024-03-06T03:03:29Z |
| format | Article |
| id | ums.eprints-25475 |
| institution | Universiti Malaysia Sabah |
| language | English English |
| last_indexed | 2024-03-06T03:03:29Z |
| publishDate | 2019 |
| record_format | dspace |
| spelling | ums.eprints-254752020-06-02T08:56:24Z https://eprints.ums.edu.my/id/eprint/25475/ Aaptamine-related alkaloid from the marine sponge Aaptos aaptos Toshiyuki Hamada Yoshito Matsumoto Phan, Chin Soon Takashi Kamada Satoaki Onitsuka Hiroaki Okamura Tetsuo Iwagawa Naomichi Arima Fumito Tani Charles S. Vairappan SH Aquaculture. Fisheries. Angling A new aaptamine-related alkaloid, 1,3-dioxolo [4,5-d] benzo [de]-1,6-naphthyridine (methylenedioxyaaptamine, 1), was isolated from the organic extracts of the Bornean marine sponge Aaptos aaptos, together with a known aaptamine derivative, 8,9,9-trimethoxy-9H-benzo [de]-1,6-naphthyridine (2). The structure of compound 1 was elucidated by interpretation of its spectroscopic data. Two compounds were tested for their cytotoxic potentials against adult T-cell leukemia (ATL) cells, and compound 1 showed moderate cytotoxic potential. 2019 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/25475/1/Aaptamine-related%20alkaloid%20from%20the%20marine%20sponge%20Aaptos%20aaptos.pdf text en https://eprints.ums.edu.my/id/eprint/25475/2/Aaptamine-related%20alkaloid%20from%20the%20marine%20sponge%20Aaptos%20aaptos%201.pdf Toshiyuki Hamada and Yoshito Matsumoto and Phan, Chin Soon and Takashi Kamada and Satoaki Onitsuka and Hiroaki Okamura and Tetsuo Iwagawa and Naomichi Arima and Fumito Tani and Charles S. Vairappan (2019) Aaptamine-related alkaloid from the marine sponge Aaptos aaptos. Natural Product Communications, 4 (9). pp. 1-3. https://doi.org/10.1177/1934578X19863935 |
| spellingShingle | SH Aquaculture. Fisheries. Angling Toshiyuki Hamada Yoshito Matsumoto Phan, Chin Soon Takashi Kamada Satoaki Onitsuka Hiroaki Okamura Tetsuo Iwagawa Naomichi Arima Fumito Tani Charles S. Vairappan Aaptamine-related alkaloid from the marine sponge Aaptos aaptos |
| title | Aaptamine-related alkaloid from the marine sponge Aaptos aaptos |
| title_full | Aaptamine-related alkaloid from the marine sponge Aaptos aaptos |
| title_fullStr | Aaptamine-related alkaloid from the marine sponge Aaptos aaptos |
| title_full_unstemmed | Aaptamine-related alkaloid from the marine sponge Aaptos aaptos |
| title_short | Aaptamine-related alkaloid from the marine sponge Aaptos aaptos |
| title_sort | aaptamine related alkaloid from the marine sponge aaptos aaptos |
| topic | SH Aquaculture. Fisheries. Angling |
| url | https://eprints.ums.edu.my/id/eprint/25475/1/Aaptamine-related%20alkaloid%20from%20the%20marine%20sponge%20Aaptos%20aaptos.pdf https://eprints.ums.edu.my/id/eprint/25475/2/Aaptamine-related%20alkaloid%20from%20the%20marine%20sponge%20Aaptos%20aaptos%201.pdf |
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