New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas
Three new halogenated tricyclic sesquiterpenes, omphalaurediol (1), rhodolaurenones B (2) and C (3) were isolated together with nine known haloganated sesquiterpenes such as rhodolaurenone A (4), rhodolaureol (5), isorhodolaureol (6), (−)-laurencenone D (7), elatol (8), (+)-deschloroelatol (9), cart...
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Language: | English |
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Taylor & Francis
2019
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Online Access: | https://eprints.ums.edu.my/id/eprint/25481/1/New%20anti-bacterial%20halogenated%20tricyclic%20sesquiterpenes%20from%20Bornean%C2%A0Laurencia%20majuscula%C2%A0%28Harvey%29%20Lucas.pdf |
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author | Takashi Kamada Phan, Chin Soon Charles Santhanaraju Vairappan |
author_facet | Takashi Kamada Phan, Chin Soon Charles Santhanaraju Vairappan |
author_sort | Takashi Kamada |
collection | UMS |
description | Three new halogenated tricyclic sesquiterpenes, omphalaurediol (1), rhodolaurenones B (2) and C (3) were isolated together with nine known haloganated sesquiterpenes such as rhodolaurenone A (4), rhodolaureol (5), isorhodolaureol (6), (−)-laurencenone D (7), elatol (8), (+)-deschloroelatol (9), cartilagineol (10), (+)-laurencenone B (11) and 2-chloro-3-hydroxy-α-chamigren-9-one (12) from a population of Bornean red algae Laurencia majuscula. The structures of three new metabolites were determined based on their spectroscopic data (IR, 1D and 2D NMR, and MS). These compounds showed antibacterial activity against three human pathogenic bacteria (Escherichia coli, Salmonella typhi and Vibrio cholera). |
first_indexed | 2024-03-06T03:03:30Z |
format | Article |
id | ums.eprints-25481 |
institution | Universiti Malaysia Sabah |
language | English |
last_indexed | 2024-03-06T03:03:30Z |
publishDate | 2019 |
publisher | Taylor & Francis |
record_format | dspace |
spelling | ums.eprints-254812020-06-04T23:31:08Z https://eprints.ums.edu.my/id/eprint/25481/ New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas Takashi Kamada Phan, Chin Soon Charles Santhanaraju Vairappan SB Plant culture SH Aquaculture. Fisheries. Angling Three new halogenated tricyclic sesquiterpenes, omphalaurediol (1), rhodolaurenones B (2) and C (3) were isolated together with nine known haloganated sesquiterpenes such as rhodolaurenone A (4), rhodolaureol (5), isorhodolaureol (6), (−)-laurencenone D (7), elatol (8), (+)-deschloroelatol (9), cartilagineol (10), (+)-laurencenone B (11) and 2-chloro-3-hydroxy-α-chamigren-9-one (12) from a population of Bornean red algae Laurencia majuscula. The structures of three new metabolites were determined based on their spectroscopic data (IR, 1D and 2D NMR, and MS). These compounds showed antibacterial activity against three human pathogenic bacteria (Escherichia coli, Salmonella typhi and Vibrio cholera). Taylor & Francis 2019 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/25481/1/New%20anti-bacterial%20halogenated%20tricyclic%20sesquiterpenes%20from%20Bornean%C2%A0Laurencia%20majuscula%C2%A0%28Harvey%29%20Lucas.pdf Takashi Kamada and Phan, Chin Soon and Charles Santhanaraju Vairappan (2019) New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas. Natural Product Research: Formerly Natural Product Letters, 33 (4). pp. 464-471. ISSN 1478-6419 (Print), 1478-6427 (Online) https://doi.org/10.1080/14786419.2017.1396593 |
spellingShingle | SB Plant culture SH Aquaculture. Fisheries. Angling Takashi Kamada Phan, Chin Soon Charles Santhanaraju Vairappan New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas |
title | New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas |
title_full | New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas |
title_fullStr | New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas |
title_full_unstemmed | New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas |
title_short | New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas |
title_sort | new anti bacterial halogenated tricyclic sesquiterpenes from bornean laurencia majuscula harvey lucas |
topic | SB Plant culture SH Aquaculture. Fisheries. Angling |
url | https://eprints.ums.edu.my/id/eprint/25481/1/New%20anti-bacterial%20halogenated%20tricyclic%20sesquiterpenes%20from%20Bornean%C2%A0Laurencia%20majuscula%C2%A0%28Harvey%29%20Lucas.pdf |
work_keys_str_mv | AT takashikamada newantibacterialhalogenatedtricyclicsesquiterpenesfromborneanlaurenciamajusculaharveylucas AT phanchinsoon newantibacterialhalogenatedtricyclicsesquiterpenesfromborneanlaurenciamajusculaharveylucas AT charlessanthanarajuvairappan newantibacterialhalogenatedtricyclicsesquiterpenesfromborneanlaurenciamajusculaharveylucas |