New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas

Three new halogenated tricyclic sesquiterpenes, omphalaurediol (1), rhodolaurenones B (2) and C (3) were isolated together with nine known haloganated sesquiterpenes such as rhodolaurenone A (4), rhodolaureol (5), isorhodolaureol (6), (−)-laurencenone D (7), elatol (8), (+)-deschloroelatol (9), cart...

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Main Authors: Takashi Kamada, Phan, Chin Soon, Charles Santhanaraju Vairappan
Format: Article
Language:English
Published: Taylor & Francis 2019
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/25481/1/New%20anti-bacterial%20halogenated%20tricyclic%20sesquiterpenes%20from%20Bornean%C2%A0Laurencia%20majuscula%C2%A0%28Harvey%29%20Lucas.pdf
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author Takashi Kamada
Phan, Chin Soon
Charles Santhanaraju Vairappan
author_facet Takashi Kamada
Phan, Chin Soon
Charles Santhanaraju Vairappan
author_sort Takashi Kamada
collection UMS
description Three new halogenated tricyclic sesquiterpenes, omphalaurediol (1), rhodolaurenones B (2) and C (3) were isolated together with nine known haloganated sesquiterpenes such as rhodolaurenone A (4), rhodolaureol (5), isorhodolaureol (6), (−)-laurencenone D (7), elatol (8), (+)-deschloroelatol (9), cartilagineol (10), (+)-laurencenone B (11) and 2-chloro-3-hydroxy-α-chamigren-9-one (12) from a population of Bornean red algae Laurencia majuscula. The structures of three new metabolites were determined based on their spectroscopic data (IR, 1D and 2D NMR, and MS). These compounds showed antibacterial activity against three human pathogenic bacteria (Escherichia coli, Salmonella typhi and Vibrio cholera).
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spelling ums.eprints-254812020-06-04T23:31:08Z https://eprints.ums.edu.my/id/eprint/25481/ New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas Takashi Kamada Phan, Chin Soon Charles Santhanaraju Vairappan SB Plant culture SH Aquaculture. Fisheries. Angling Three new halogenated tricyclic sesquiterpenes, omphalaurediol (1), rhodolaurenones B (2) and C (3) were isolated together with nine known haloganated sesquiterpenes such as rhodolaurenone A (4), rhodolaureol (5), isorhodolaureol (6), (−)-laurencenone D (7), elatol (8), (+)-deschloroelatol (9), cartilagineol (10), (+)-laurencenone B (11) and 2-chloro-3-hydroxy-α-chamigren-9-one (12) from a population of Bornean red algae Laurencia majuscula. The structures of three new metabolites were determined based on their spectroscopic data (IR, 1D and 2D NMR, and MS). These compounds showed antibacterial activity against three human pathogenic bacteria (Escherichia coli, Salmonella typhi and Vibrio cholera). Taylor & Francis 2019 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/25481/1/New%20anti-bacterial%20halogenated%20tricyclic%20sesquiterpenes%20from%20Bornean%C2%A0Laurencia%20majuscula%C2%A0%28Harvey%29%20Lucas.pdf Takashi Kamada and Phan, Chin Soon and Charles Santhanaraju Vairappan (2019) New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas. Natural Product Research: Formerly Natural Product Letters, 33 (4). pp. 464-471. ISSN 1478-6419 (Print), 1478-6427 (Online) https://doi.org/10.1080/14786419.2017.1396593
spellingShingle SB Plant culture
SH Aquaculture. Fisheries. Angling
Takashi Kamada
Phan, Chin Soon
Charles Santhanaraju Vairappan
New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas
title New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas
title_full New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas
title_fullStr New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas
title_full_unstemmed New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas
title_short New anti-bacterial halogenated tricyclic sesquiterpenes from Bornean Laurencia majuscula (Harvey) Lucas
title_sort new anti bacterial halogenated tricyclic sesquiterpenes from bornean laurencia majuscula harvey lucas
topic SB Plant culture
SH Aquaculture. Fisheries. Angling
url https://eprints.ums.edu.my/id/eprint/25481/1/New%20anti-bacterial%20halogenated%20tricyclic%20sesquiterpenes%20from%20Bornean%C2%A0Laurencia%20majuscula%C2%A0%28Harvey%29%20Lucas.pdf
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