15-Deoxy-Isoxeniolide-A, New Diterpenoid from a Bornean Soft Coral, Xenia sp.

A new xenicane diterpenoid, 15-deoxy-isoxeniolide-A (1) along with four known compounds 9-deoxy-isoxeniolide-A (2), isoxeniolide-A (3), xeniolide-A (4) and coraxeniolide-B (5) were isolated from the Bornean soft coral Xenia sp. The structure of this metabolite was elucidated on the basis of spectral...

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Bibliographic Details
Main Authors: Chin-Soon Phan, Takashi Kamada, Kazushi Kobayashi, Toshiyuki Hamada, Charles Santhanaraju Vairappan
Format: Article
Language:English
English
Published: 2018
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/25549/2/15-Deoxy-Isoxeniolide-A%2C%20New%20Diterpenoid%20from%20a%20Bornean%20Soft%20Coral%2C%20Xenia%20sp..pdf
https://eprints.ums.edu.my/id/eprint/25549/1/15-Deoxy-Isoxeniolide-A%2C%20New%20Diterpenoid%20from%20a%20Bornean%20Soft%20Coral%2C%20Xenia%20sp.1.pdf
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Summary:A new xenicane diterpenoid, 15-deoxy-isoxeniolide-A (1) along with four known compounds 9-deoxy-isoxeniolide-A (2), isoxeniolide-A (3), xeniolide-A (4) and coraxeniolide-B (5) were isolated from the Bornean soft coral Xenia sp. The structure of this metabolite was elucidated on the basis of spectral analysis NMR and HRESIMS. Compound 5 showed potent cytotoxic activity against ATL cell line, S1T.