Multiple molecular targets mediated antioxidant activity, molecular docking, ADMET, QSAR and bioactivity studies of halo substituted urea derivatives of α-Methyl-l-DOPA
A series of novel α-methyl-l-DOPA urea derivatives viz., 3-(3,4-dihydroxyphenyl)-2-methyl-2-(3-halo/trifluoromethyl substituted phenyl ureido)propanoic acids (6a-e) have been synthesized from the reaction of α-methyl-l-DOPA (3) with various aryl isocyanates (4a-e) by using triethylamine (5, TEA) as...
相似书籍
-
Hunig's base catalyzed synthesis of new 1-(2,3-dihydro-1H-inden-1-yl)-3-aryl urea/ thiourea derivatives as potent antioxidants and 2HCK enzyme growth inhibitors
由: Venkataramana Lachhi Reddy, et al.
出版: (2020) -
An in silico ADMET, molecular docking study and microwave-assisted synthesis of new phosphorylated derivatives of thiazolidinedione as potential anti-diabetic agents
由: Hanumantha Rao Addanki, et al.
出版: (2022) -
Green Synthesis, antioxidant, and plant growth regulatory Activities of Novel a-furfuryl-2-alkylaminophosphonates
由: Maheshwara Reddy Nadiveedhi, et al.
出版: (2021) -
3D-QSAR, ADMET, and molecular docking studies of aztreonam analogs as inhibitors
由: Melese Legesse Mitku, et al.
出版: (2024-08-01) -
Synthesis, in-vivo anti-diabetic & anticancer activities and molecular modelling studies of tetrahydrobenzo[d]thiazole tethered nicotinohydrazide derivatives
由: Suri Babu Patchipala, et al.
出版: (2022)