Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review

BACKGROUND: TheWorld health organization reported that 875 million children worldwide require antihelminth preventive chemotherapy annually. Vast majority of STH infections (67%) and YLDs (68%) occurred in Asia.METHODS: A systematic search was performed for relevant titles, abstract, and keywords fr...

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Main Authors: M. Mohd Faizal, B. P. Anaanthan, M. Nur Ezdiani, M. N. Azmawati, A. Norfazilah, F. G. Hasanain, Mohammad Saffree Jeffree, Syed Sharizman Syed Abdul Rahim, Mohd Rohaizat Hassan
Format: Article
Language:English
English
Published: 2020
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/25940/1/Efficacy%20of%20Albendazole%20Against%20Soil-transmitted%20Helminthiasis%20among%20Children%20in%20Asia.pdf
https://eprints.ums.edu.my/id/eprint/25940/2/Efficacy%20of%20Albendazole%20Against%20Soil-transmitted%20Helminthiasis%20among%20Children%20in%20Asia1.pdf
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author M. Mohd Faizal
B. P. Anaanthan
M. Nur Ezdiani
M. N. Azmawati
A. Norfazilah
F. G. Hasanain
Mohammad Saffree Jeffree
Syed Sharizman Syed Abdul Rahim
Mohd Rohaizat Hassan
author_facet M. Mohd Faizal
B. P. Anaanthan
M. Nur Ezdiani
M. N. Azmawati
A. Norfazilah
F. G. Hasanain
Mohammad Saffree Jeffree
Syed Sharizman Syed Abdul Rahim
Mohd Rohaizat Hassan
author_sort M. Mohd Faizal
collection UMS
description BACKGROUND: TheWorld health organization reported that 875 million children worldwide require antihelminth preventive chemotherapy annually. Vast majority of STH infections (67%) and YLDs (68%) occurred in Asia.METHODS: A systematic search was performed for relevant titles, abstract, and keywords from Cochrane Library, PubMed, and Scopus around October 2018 based on the PICO strategy. Out of 173 papers that were evaluated, final assessment for eligibility had yielded a total of five papers to be included for analysis covering period from 2013 to 2018.RESULTS: Of the five selected studies, three were randomized controlled trial, one was cohort and another one was described more like a quasi-experimental trial. All infection intensity showed improvement post-intervention. Four of the five studies used Kato Katz as diagnostic method with one combined it with Baermann techniques. One used McMaster egg counting method. All except one study tested albendazole efficacy in their study either alone or in combination with other chemotherapy such as diethyl carbazide or combining with education pamphlet. Egg reduction rate was reported as low as 63% and as high as 99.9%.
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spelling ums.eprints-259402021-04-08T14:40:49Z https://eprints.ums.edu.my/id/eprint/25940/ Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review M. Mohd Faizal B. P. Anaanthan M. Nur Ezdiani M. N. Azmawati A. Norfazilah F. G. Hasanain Mohammad Saffree Jeffree Syed Sharizman Syed Abdul Rahim Mohd Rohaizat Hassan R Medicine (General) BACKGROUND: TheWorld health organization reported that 875 million children worldwide require antihelminth preventive chemotherapy annually. Vast majority of STH infections (67%) and YLDs (68%) occurred in Asia.METHODS: A systematic search was performed for relevant titles, abstract, and keywords from Cochrane Library, PubMed, and Scopus around October 2018 based on the PICO strategy. Out of 173 papers that were evaluated, final assessment for eligibility had yielded a total of five papers to be included for analysis covering period from 2013 to 2018.RESULTS: Of the five selected studies, three were randomized controlled trial, one was cohort and another one was described more like a quasi-experimental trial. All infection intensity showed improvement post-intervention. Four of the five studies used Kato Katz as diagnostic method with one combined it with Baermann techniques. One used McMaster egg counting method. All except one study tested albendazole efficacy in their study either alone or in combination with other chemotherapy such as diethyl carbazide or combining with education pamphlet. Egg reduction rate was reported as low as 63% and as high as 99.9%. 2020 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/25940/1/Efficacy%20of%20Albendazole%20Against%20Soil-transmitted%20Helminthiasis%20among%20Children%20in%20Asia.pdf text en https://eprints.ums.edu.my/id/eprint/25940/2/Efficacy%20of%20Albendazole%20Against%20Soil-transmitted%20Helminthiasis%20among%20Children%20in%20Asia1.pdf M. Mohd Faizal and B. P. Anaanthan and M. Nur Ezdiani and M. N. Azmawati and A. Norfazilah and F. G. Hasanain and Mohammad Saffree Jeffree and Syed Sharizman Syed Abdul Rahim and Mohd Rohaizat Hassan (2020) Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review. Open Access Macedonian Journal of Medical Sciences, 8. pp. 70-77. ISSN 1857-9655 https://doi.org/10.3889/oamjms.2020.4305
spellingShingle R Medicine (General)
M. Mohd Faizal
B. P. Anaanthan
M. Nur Ezdiani
M. N. Azmawati
A. Norfazilah
F. G. Hasanain
Mohammad Saffree Jeffree
Syed Sharizman Syed Abdul Rahim
Mohd Rohaizat Hassan
Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review
title Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review
title_full Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review
title_fullStr Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review
title_full_unstemmed Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review
title_short Efficacy of Albendazole Against Soil-transmitted Helminthiasis among Children in Asia: Systematic Review
title_sort efficacy of albendazole against soil transmitted helminthiasis among children in asia systematic review
topic R Medicine (General)
url https://eprints.ums.edu.my/id/eprint/25940/1/Efficacy%20of%20Albendazole%20Against%20Soil-transmitted%20Helminthiasis%20among%20Children%20in%20Asia.pdf
https://eprints.ums.edu.my/id/eprint/25940/2/Efficacy%20of%20Albendazole%20Against%20Soil-transmitted%20Helminthiasis%20among%20Children%20in%20Asia1.pdf
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