Advanced Triple Negative Breast Cancer in Pregnancy

Breast cancer is one of the most common prevalent malignancies in pregnancy. The management is challenging as it involves both maternal and fetal well-being. A 41-year-old lady was diagnosed with triple negative breast cancer in the second trimester pregnancy. Neoadjuvant chemotherapy was decided as...

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Main Authors: Tze Huat Chong, Gunaseelan G. Durairaj, Firdaus Hayati, Nornazirah Azizan, Fatimah Ahmedy, Nor Faezan Abdul Rashid
Format: Article
Language:English
English
Published: 2020
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/26305/1/Advanced%20Triple%20Negative%20Breast%20Cancer%20in%20Pregnancy.pdf
https://eprints.ums.edu.my/id/eprint/26305/2/Advanced%20Triple%20Negative%20Breast%20Cancer%20in%20Pregnancy1.pdf
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author Tze Huat Chong
Gunaseelan G. Durairaj
Firdaus Hayati
Nornazirah Azizan
Fatimah Ahmedy
Nor Faezan Abdul Rashid
author_facet Tze Huat Chong
Gunaseelan G. Durairaj
Firdaus Hayati
Nornazirah Azizan
Fatimah Ahmedy
Nor Faezan Abdul Rashid
author_sort Tze Huat Chong
collection UMS
description Breast cancer is one of the most common prevalent malignancies in pregnancy. The management is challenging as it involves both maternal and fetal well-being. A 41-year-old lady was diagnosed with triple negative breast cancer in the second trimester pregnancy. Neoadjuvant chemotherapy was decided as she opted for a continuation of pregnancy and refusal for mastectomy. After completing the second cycle of chemotherapy, she developed preterm premature rupture of membrane and had fetal malposition requiring an emergency caesarean section. Computed tomography staging revealed an advanced disease, hence needing palliative treatment and support. The difficulties in managing this case arise in choosing the best treatment to preserve both maternal and fetal wellbeing.
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spelling ums.eprints-263052020-11-19T04:01:45Z https://eprints.ums.edu.my/id/eprint/26305/ Advanced Triple Negative Breast Cancer in Pregnancy Tze Huat Chong Gunaseelan G. Durairaj Firdaus Hayati Nornazirah Azizan Fatimah Ahmedy Nor Faezan Abdul Rashid R Medicine (General) Breast cancer is one of the most common prevalent malignancies in pregnancy. The management is challenging as it involves both maternal and fetal well-being. A 41-year-old lady was diagnosed with triple negative breast cancer in the second trimester pregnancy. Neoadjuvant chemotherapy was decided as she opted for a continuation of pregnancy and refusal for mastectomy. After completing the second cycle of chemotherapy, she developed preterm premature rupture of membrane and had fetal malposition requiring an emergency caesarean section. Computed tomography staging revealed an advanced disease, hence needing palliative treatment and support. The difficulties in managing this case arise in choosing the best treatment to preserve both maternal and fetal wellbeing. 2020 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/26305/1/Advanced%20Triple%20Negative%20Breast%20Cancer%20in%20Pregnancy.pdf text en https://eprints.ums.edu.my/id/eprint/26305/2/Advanced%20Triple%20Negative%20Breast%20Cancer%20in%20Pregnancy1.pdf Tze Huat Chong and Gunaseelan G. Durairaj and Firdaus Hayati and Nornazirah Azizan and Fatimah Ahmedy and Nor Faezan Abdul Rashid (2020) Advanced Triple Negative Breast Cancer in Pregnancy. GMJ, 31. pp. 663-665. http://dx.doi.org/10.12996/gmj.2020.153
spellingShingle R Medicine (General)
Tze Huat Chong
Gunaseelan G. Durairaj
Firdaus Hayati
Nornazirah Azizan
Fatimah Ahmedy
Nor Faezan Abdul Rashid
Advanced Triple Negative Breast Cancer in Pregnancy
title Advanced Triple Negative Breast Cancer in Pregnancy
title_full Advanced Triple Negative Breast Cancer in Pregnancy
title_fullStr Advanced Triple Negative Breast Cancer in Pregnancy
title_full_unstemmed Advanced Triple Negative Breast Cancer in Pregnancy
title_short Advanced Triple Negative Breast Cancer in Pregnancy
title_sort advanced triple negative breast cancer in pregnancy
topic R Medicine (General)
url https://eprints.ums.edu.my/id/eprint/26305/1/Advanced%20Triple%20Negative%20Breast%20Cancer%20in%20Pregnancy.pdf
https://eprints.ums.edu.my/id/eprint/26305/2/Advanced%20Triple%20Negative%20Breast%20Cancer%20in%20Pregnancy1.pdf
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